Publication	Data		Fish	Anatomy
Kesavan et al., 2020	Fig. 2		fgf8ati282a/+ ,   fgf8ati282a/ti282a	forebrain ism1 expression absent, abnormal forebrain neural rod ism1 expression absent, abnormal midbrain hindbrain boundary neural rod ism1 expression absent, abnormal midbrain hindbrain boundary neural rod ism1 expression decreased amount, abnormal
Gebuijs et al., 2019	Fig. 2.		fgf8ati282a/+ ,   fgf8ati282a/ti282a	ceratobranchial 5 bone bone mineralization decreased occurrence, abnormal head decreased size, abnormal parasphenoid bone mineralization decreased occurrence, abnormal
	Fig. 3		fgf8ati282a/+ ,   fgf8ati282a/ti282a	ceratohyal bone decreased length, abnormal ethmoid cartilage decreased length, abnormal head anterior region decreased width, abnormal head decreased size, abnormal Meckel's cartilage decreased length, abnormal Meckel's cartilage-palatoquadrate cartilage joint decreased width, abnormal
	Fig. 4		fgf8ati282a/+ ,   fgf8ati282a/ti282a	branchiostegal ray 1 bone mineralization decreased occurrence, abnormal ceratobranchial 5 bone bone mineralization decreased occurrence, abnormal ceratobranchial 5 tooth bone mineralization decreased occurrence, abnormal cleithrum bone mineralization decreased occurrence, abnormal entopterygoid bone mineralization decreased occurrence, abnormal notochord bone mineralization decreased occurrence, abnormal opercle bone mineralization decreased occurrence, abnormal otolith bone mineralization decreased occurrence, abnormal parasphenoid bone mineralization decreased occurrence, abnormal
	Fig. 5		fgf8ati282a/ti282a	whole organism col1a1a expression decreased amount, abnormal whole organism col9a1b expression decreased amount, abnormal whole organism dlx2a expression increased amount, abnormal whole organism fgf8a expression increased amount, abnormal whole organism nkx3-2 expression increased amount, abnormal whole organism runx2a expression increased amount, abnormal whole organism sp7 expression increased amount, abnormal
	Fig. 6.		fgf8ati282a/ti282a	whole organism dlx2a expression absent, abnormal whole organism runx2a expression increased amount, abnormal
Nittoli et al., 2019	Fig. 8		fgf8ati282a/ti282a	somite uncx4.1 expression increased distribution, abnormal somite uncx expression increased distribution, abnormal
Roberson et al., 2017	Fig. 5		fgf8ati282a/ti282a	diencephalon dorsal region dbx1b expression decreased amount, abnormal
	Fig. 6		fgf8ati282a/ti282a	diencephalon dorsal region ackr3b expression decreased distribution, abnormal diencephalon dorsal region cxcl12b expression decreased distribution, abnormal
Zhang et al., 2017	Fig. 1		AB + MO1-fgf8a	midbrain posterior side otx2b expression increased distribution, abnormal
	Fig. 2		AB + MO1-fgf8a	eye pax6a expression decreased amount, abnormal forebrain pax6a expression decreased amount, abnormal hindbrain pax6a expression decreased amount, abnormal midbrain pax6a expression mislocalised, abnormal
	Fig. 3		AB + MO1-fgf8a	midbrain posterior region epha4a expression mislocalised, abnormal
	Fig. 5		AB + MO1-fgf8a	midbrain hindbrain boundary pax2a expression absent, abnormal midbrain hindbrain boundary morphology, abnormal
	Fig. 7		AB + MO1-fgf8a	midbrain hindbrain boundary wnt1 expression absent, abnormal
	Fig. 8		AB + MO1-fgf8a	midbrain hindbrain boundary en2b expression absent, abnormal midbrain posterior region en2b expression absent, abnormal
Akiyama et al., 2014	Fig. S1		fgf8ati282a/ti282a	segmental plate ab2-mapk labeling decreased amount, abnormal somitogenesis process quality, abnormal
Choe et al., 2014	Fig. 4		fgf8ati282a/ti282a	ceratobranchial cartilage decreased amount, abnormal pharyngeal pouch decreased amount, abnormal
	Fig. 5		fgf8ati282a/ti282a; el72Tg; pt6Tg	pharyngeal pouch epithelial cell migration process quality, abnormal pharyngeal pouch pharyngeal system development process quality, abnormal
Dean et al., 2014	Fig. 4		fgf8ax15/x15	dorsal habenular nucleus poorly differentiated, abnormal habenula development decreased process quality, abnormal
Maier et al., 2014	Fig. 3		fgf8ati282a/ti282a	otic vesicle decreased size, abnormal posterior macula decreased size, abnormal posterior macula has fewer parts of type hair cell, abnormal
Maulding et al., 2014	Fig. 3		fgf8ax15/x15	otic placode decreased size, abnormal otic vesicle decreased size, abnormal
Clanton et al., 2013	Fig. 2		fgf8ax15/x15	parapineal organ has fewer parts of type cell, abnormal
	Fig. 4		fgf8ax15/x15; zf104Tg	parapineal organ malformed, abnormal pineal complex has extra parts of type photoreceptor cell, abnormal
	Fig. 7		fgf8ax15/x15; zf104Tg ,   fgf8ax15/x15	parapineal organ has fewer parts of type cell, abnormal pineal complex has extra parts of type photoreceptor cell, abnormal
Dworkin et al., 2012	Fig. 6		WT + MO3-fgf8a	brain apoptotic, abnormal cerebellum absent, abnormal ventricular system morphology, abnormal
Clément et al., 2011	Fig. 7		fgf8ax15/+ ,   fgf8ax15/x15	Kupffer's vesicle cilium decreased length, abnormal
Kapsimali et al., 2011	Fig. 2		fgf8ati282a/ti282a	fibroblast growth factor receptor signaling pathway process quality, abnormal oral epithelium has fewer parts of type taste bud, abnormal taste bud formation decreased process quality, abnormal
Liu et al., 2011	Fig. 4		WT + MO3-fgf8a	Kupffer's vesicle cilium decreased amount, abnormal Kupffer's vesicle cilium decreased length, abnormal
Matsui et al., 2011	Fig. 3		WT + MO3-fgf8a	forerunner cell group distributed, abnormal
de Pater et al., 2009	Fig. 6		f2Tg/+; twu26Tg/+ + MO2-fgf8a	cardiac ventricle cardiac muscle cell decreased amount, abnormal heart decreased size, abnormal
Hong et al., 2009	Fig. 5		AB + MO1-fgf8a	Kupffer's vesicle cilium decreased amount, abnormal
Kwon et al., 2009	Fig. 1		fgf8ati282a/ti282a	otic vesicle decreased size, abnormal otic vesicle malformed, abnormal
	Fig. 2		fgf8ati282a/ti282a	otic placode formation process quality, abnormal
McMahon et al., 2009	Fig. 11		fgf8ati282a/ti282a	retina development in camera-type eye disrupted, abnormal
Picker et al., 2009	Fig. 1		fgf8ati282a/ti282a	embryonic retina morphogenesis in camera-type eye decreased process quality, abnormal optic cup physical object quality, abnormal
Komisarczuk et al., 2008	Fig. 6		fgf8ati282a/ti282a	central nervous system development disrupted, abnormal
Leucht et al., 2008	Fig. 4		fgf8ati282a/ti282a; ne1939Tg	cell proliferation in hindbrain disrupted, abnormal cell proliferation in midbrain disrupted, abnormal
Marques et al., 2008	Fig. 1		fgf8ati282a/ti282a; f2Tg	atrium cardiac muscle cell decreased amount, abnormal cardiac ventricle cardiac muscle cell decreased amount, abnormal heart decreased size, abnormal heart development disrupted, abnormal heart shape, abnormal
	Fig. 2		fgf8ati282a/ti282a	heart rudiment decreased size, abnormal
Sperber et al., 2008	Fig. 8		fgf8ati282a/ti282a	cartilage development disrupted, abnormal determination of left/right symmetry disrupted, abnormal pharyngeal arch 3-7 morphology, abnormal
Albertson et al., 2007	Fig. 2		fgf8ati282a/+	chondrocranium bilateral symmetry, abnormal ventral mandibular arch bilateral symmetry, abnormal ventral mandibular arch malformed, abnormal
	Fig. 3		fgf8ati282a/+	opercle bilateral symmetry, abnormal opercle malformed, abnormal
	Fig. 5		fgf8ati282a/+	regulation of bone remodeling occurrence, abnormal ventral mandibular arch malformed, abnormal
Hans et al., 2007	Fig. 5		fgf8ati282a/ti282a	otic vesicle decreased size, abnormal
Molina et al., 2007	Fig. 3		pt6Tg + MO3-fgf8a	midbrain hindbrain boundary morphology, abnormal otic vesicle morphology, abnormal retina morphology, abnormal
	Fig. 4		fgf8ati282a/ti282a; pt6Tg	lens morphology, abnormal midbrain hindbrain boundary morphology, abnormal retina morphology, abnormal
Nechiporuk et al., 2007	Fig. 5		fgf8ati282a/ti282a	midbrain hindbrain boundary morphology, abnormal midbrain-hindbrain boundary development disrupted, abnormal
Plaster et al., 2007	Fig. 4		fgf8ati282a/ti282a	pharyngeal arch 3-7 skeleton disorganized, abnormal pharyngeal arch morphology, abnormal
Wendl et al., 2007	Fig. 6		fgf8ati282a/ti282a	thyroid primordium decreased size, abnormal
Phenotype Annotation (1994-2006)	Fig. for (ti282a)		fgf8ati282a/ti282a	anatomical system quality, abnormal brain quality, abnormal inner ear quality, abnormal midbrain hindbrain boundary quality, abnormal midbrain quality, abnormal nervous system quality, abnormal pharyngeal arch 3-7 skeleton quality, abnormal sensory system quality, abnormal whole organism lethal (sensu genetics), abnormal
Mackereth et al., 2005	Fig. 4		fgf8ati282a/ti282a	otic placode physical object quality, abnormal otic vesicle decreased size, abnormal otic vesicle morphogenesis process quality, abnormal
	Fig. 7		fgf8ati282a/ti282a	otic vesicle decreased size, abnormal otic vesicle has fewer parts of type otolith, abnormal otic vesicle morphogenesis process quality, abnormal
Jászai et al., 2003	Fig. 1		fgf8ati282a/ti282a	cerebellum development disrupted, abnormal midbrain hindbrain boundary aplastic, abnormal midbrain hindbrain boundary neural rod morphology, abnormal midbrain-hindbrain boundary development disrupted, abnormal optic tectum increased size, abnormal
	Fig. 2		fgf8ati282a/ti282a	alar plate midbrain region morphology, abnormal midbrain hindbrain boundary neural rod morphology, abnormal midbrain morphology, abnormal midbrain neural rod morphology, abnormal midbrain-hindbrain boundary development disrupted, abnormal
	Fig. 3		fgf8ati282a/ti282a	cerebellum development disrupted, abnormal cerebellum morphology, abnormal midbrain hindbrain boundary aplastic, abnormal midbrain-hindbrain boundary development disrupted, abnormal
	Fig. 4		fgf8ati282a/ti282a	locus coeruleus aplastic, abnormal midbrain hindbrain boundary aplastic, abnormal midbrain-hindbrain boundary development disrupted, abnormal rhombomere 1 morphology, abnormal rhombomere 3 decreased thickness, abnormal rhombomere 5 decreased thickness, abnormal rostrocaudal neural tube patterning disrupted, abnormal
	Fig. 5		fgf8ati282a/ti282a	apoptotic process increased occurrence, abnormal cell proliferation in hindbrain disrupted, abnormal cell proliferation in midbrain disrupted, abnormal hindbrain apoptotic, abnormal optic tectum apoptotic, abnormal
Lam et al., 2003	Fig. 6		fgf8ati282a/ti282a	locus coeruleus neuron decreased amount, abnormal
Araki et al., 2001	Fig. 1		WT + MO3-fgf8a ,   fgf8ati282a/ti282a	cerebellum aplastic, abnormal midbrain hindbrain boundary aplastic, abnormal
Kudoh et al., 2001	Fig. 3		fgf8aunspecified/unspecified	optic tectum physical object quality, abnormal
Adamska et al., 2000	Fig. 3		fgf8ati282a/ti282a	otic vesicle hmx3a expression decreased amount, abnormal statoacoustic (VIII) ganglion hmx3a expression absent, abnormal
Reifers et al., 2000	Fig. 1		fgf8ati282a/ti282a	anterior cardinal vein absent, abnormal blood circulation decreased functionality, abnormal brain vasculature dorsal region absent, abnormal cardiac ventricle decreased length, abnormal cardiac ventricle hypotrophic, abnormal heart decreased length, abnormal heart development process quality, abnormal heart dysplastic, abnormal heart morphology, abnormal hindbrain blood vessel absent, abnormal intersegmental vessel absent, abnormal midbrain hindbrain boundary blood vessel absent, abnormal optic tectum blood vessel absent, abnormal pharyngeal arch blood vessel absent, abnormal
Guo et al., 1999	Fig. 6		fgf8ati282a/ti282a	locus ceruleus development disrupted, abnormal locus coeruleus absent, abnormal
Heisenberg et al., 1999	Fig. 9		fgf8ati282a/ti282a	cerebellum aplastic, abnormal
Reifers et al., 1998	Fig. 10		fgf8ati282a/ti282a	somite development decreased process quality, abnormal somite poorly differentiated, abnormal
	Fig. 7		fgf8ati282a/ti282a	cerebellum development decreased process quality, abnormal midbrain-hindbrain boundary development decreased process quality, abnormal whole organism lacks all parts of type cerebellum, abnormal whole organism lacks all parts of type midbrain hindbrain boundary, abnormal
	Fig. 8		fgf8ati282a/ti282a	midbrain hindbrain boundary physical object quality, abnormal midbrain-hindbrain boundary development decreased process quality, abnormal
Brand et al., 1996	Fig. 1		fgf8ati282a/ti282a	blood circulation disrupted, abnormal cerebellum absent, abnormal midbrain hindbrain boundary absent, abnormal optic tectum increased size, abnormal
	Fig. 7		fgf8ati282a/ti282a	cerebellum absent, abnormal inner ear decreased size, abnormal midbrain hindbrain boundary absent, abnormal midbrain neural rod increased thickness, abnormal midbrain neural rod prominent, abnormal optic tectum increased size, abnormal otolith organ has fewer parts of type otolith, abnormal semicircular canal truncated, abnormal
	Fig. 8		fgf8ati282a/ti282a	cerebellum aplastic, abnormal midbrain hindbrain boundary aplastic, abnormal optic tectum increased size, abnormal tegmentum morphology, abnormal
Brand et al., 1996	Table 1		fgf8ati282a/ti282a	post-vent region curved ventral, abnormal retinal ganglion cell axon guidance disrupted, abnormal
Whitfield et al., 1996	Table 3		fgf8ati282a/ti282a	inner ear decreased size, abnormal inner ear has fewer parts of type otolith, abnormal