FIGURE

Fig. 2

ID

ZDB-FIG-070925-52

Publication

Albertson et al., 2007 - Fgf8 haploinsufficiency results in distinct craniofacial defects in adult zebrafish

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Fig. 2

Fig. 2. Mandibular symmetry and cranial suture patterning is altered in ace^ti282a/+ zebrafish. The cranial midline was defined as the midline of the neurocranium. In homozygous wild-type zebrafish, the mandibular symphysis (m) was oriented along the cranial midline (A). In ace^ti282a/+ animals, however, the mandible exhibited pronounced asymmetry (B). The interfrontal (if) and sagittal (s) sutures in ace^ti282a/+ zebrafish also deviated significantly from the midline compared to wild-type siblings (F-ratio = 20.8, p < 0.0001, and F-ratio = 8.36, p = 0.006, respectively).

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Fish:	fgf8a^ti282a/+
Observed In:	chondrocranium ventral mandibular arch
Stage:	Adult

Phenotype Detail

Acknowledgments

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Reprinted from Developmental Biology, 306(2), Albertson, R.C., and Yelick, P.C., Fgf8 haploinsufficiency results in distinct craniofacial defects in adult zebrafish, 505-515, Copyright (2007) with permission from Elsevier. Full text @ Dev. Biol.