- Title
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Identification and expression of the family of classical protein-tyrosine phosphatases in zebrafish
- Authors
- van Eekelen, M., Overvoorde, J., van Rooijen, C., and den Hertog, J.
- Source
- Full text @ PLoS One
Expression patterns of the classical PTPs during zebrafish development. Albino zebrafish embryos were fixed at the following stages: 8 cell, 6 hpf, 10 hpf, 1 dpf, 2 dpf and 3 dpf. Whole mount in situ hybridization experiments were done with probes generated to target the classical PTPs and pictures were taken. Shown are 8 cell stage; top: lateral view, animal pole on top; bottom: animal pole view. 6 hpf; top: lateral view, animal pole on top, bottom: animal pole view. 10 hpf; top: lateral view, dorsal to the right, bottom: dorsal view anterior towards the top. 24, 48 and 72 hpf; top: lateral view anterior to the left, bottom: dorsal view anterior to the left. EXPRESSION / LABELING:
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See legend to Fig. 3. EXPRESSION / LABELING:
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See legend to Fig. 3. EXPRESSION / LABELING:
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See legend to Fig. 3. EXPRESSION / LABELING:
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See legend to Fig. 3. EXPRESSION / LABELING:
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See legend to Fig. 3. EXPRESSION / LABELING:
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See legend to Fig. 3. EXPRESSION / LABELING:
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See legend to Fig. 3. EXPRESSION / LABELING:
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See legend to Fig. 3. EXPRESSION / LABELING:
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Similar and distinct expression patterns of duplicated non-receptor PTPs. Albino zebrafish embryos were fixed at 24 hpf and whole mount in situ hybridization was done with probes generated to target (A) ptpn4a and ptpn4b or (B) ptpn9a and ptpn9b. Depicted are (top) lateral view and (bottom) dorsal view of 72 hpf embryos. EXPRESSION / LABELING:
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Overlapping and mutually exclusive expression patterns of duplicated receptor PTPs. Albino zebrafish embryos were fixed at different stages and whole mount in situ experiments were done with probes generated to target (A) ptprza and ptprzb, (B) ptprfa and ptprfb, (C) ptprna and ptprnb, (D) ptprea and ptpreb and (E) ptpreb. Depicted are (A) dorsal views of (top) 48 hpf embryos and (bottom) 72 hpf embryos, (B) (top) lateral views and (bottom) dorsal views of 48 hpf embryos, (C) lateral views of 24 hpf embryos and (D) dorsal view of 10 hpf embryos (top), lateral view of 24 hpf embryos (bottom). (E) Lateral view (left) and dorsal view (right) of the tip of the tail of 18 hpf embryos. |