Gene

ptpra

ID

ZDB-GENE-020107-1

Name

protein tyrosine phosphatase receptor type A

Symbol

ptpra Nomenclature History

Previous Names

RPTP[a] (1)
zf-RPTP[a] (1)

Type

protein_coding_gene

Location

Chr: 21 Mapping Details/Browsers

Description

Predicted to have protein tyrosine phosphatase activity. Involved in convergent extension involved in gastrulation; regulation of protein kinase activity; and retina development in camera-type eye. Predicted to localize to integral component of membrane. Is expressed in blastomere; head; nervous system; and pectoral fin. Orthologous to human PTPRA (protein tyrosine phosphatase receptor type A).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

7 figures from 4 publications

Cross-Species Comparison

High Throughput Data

GEO (1)

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Daniocell

Thisse Expression Data

No data available

Wild Type Expression Summary

Phenotype

All Phenotype Data: 6 figures from 2 publications
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With ptpra Human Ortholog

No data available

Associated With ptpra Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Active_site	IPR016130	Protein-tyrosine phosphatase, active site
Domain	IPR000242	Tyrosine-specific protein phosphatase, PTPase domain
Domain	IPR000387	Tyrosine-specific protein phosphatases domain
Domain	IPR003595	Protein-tyrosine phosphatase, catalytic
Family	IPR016336	Receptor tyrosine-protein phosphatase, alpha/epsilon-type
Family	IPR027262	Receptor tyrosine-protein phosphatase alpha
Family	IPR050348	Protein-Tyrosine Phosphatase
Homologous_superfamily	IPR029021	Protein-tyrosine phosphatase-like