Gene

ptpn4b

ID

ZDB-GENE-030131-6259

Name

protein tyrosine phosphatase non-receptor type 4b

Symbol

ptpn4b Nomenclature History

Previous Names

fi40g11
si:rp71-1n18.2
wu:fi40g11

Type

protein_coding_gene

Location

Chr: 22 Mapping Details/Browsers

Description

Predicted to have protein tyrosine phosphatase activity. Predicted to be involved in protein dephosphorylation. Predicted to localize to cytoplasm and cytoplasmic side of plasma membrane. Orthologous to human PTPN4 (protein tyrosine phosphatase non-receptor type 4).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

2 figures from van Eekelen et al., 2010

Cross-Species Comparison

High Throughput Data

GEO (1)

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Daniocell

Thisse Expression Data

No data available

Wild Type Expression Summary

Phenotype

All Phenotype Data: No data available
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With ptpn4b Human Ortholog

No data available

Associated With ptpn4b Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Active_site	IPR016130	Protein-tyrosine phosphatase, active site
Conserved_site	IPR019747	FERM conserved site
Domain	IPR000242	Tyrosine-specific protein phosphatase, PTPase domain
Domain	IPR000299	FERM domain
Domain	IPR000387	Tyrosine-specific protein phosphatases domain
Domain	IPR001478	PDZ domain
Domain	IPR003595	Protein-tyrosine phosphatase, catalytic
Domain	IPR014847	FERM adjacent
Domain	IPR018979	FERM, N-terminal
Domain	IPR018980	FERM, C-terminal PH-like domain
Domain	IPR019748	FERM central domain
Domain	IPR019749	Band 4.1 domain
Domain	IPR041783	PTPN3/4, FERM domain C-lobe
Family	IPR012151	Protein-tyrosine phosphatase, non-receptor type-3, -4
Homologous_superfamily	IPR011993	PH-like domain superfamily
Homologous_superfamily	IPR014352	FERM/acyl-CoA-binding protein superfamily
Homologous_superfamily	IPR029021	Protein-tyrosine phosphatase-like
Homologous_superfamily	IPR029071	Ubiquitin-like domain superfamily
Homologous_superfamily	IPR035963	FERM superfamily, second domain
Homologous_superfamily	IPR036034	PDZ superfamily

Domain Details Per Protein

Protein	Length	Band 4.1 domain	FERM/acyl-CoA-binding protein superfamily	FERM adjacent	FERM central domain	FERM conserved site	FERM, C-terminal PH-like domain	FERM domain	FERM, N-terminal	FERM superfamily, second domain	PDZ domain	PDZ superfamily	PH-like domain superfamily	Protein-tyrosine phosphatase, active site	Protein-tyrosine phosphatase, catalytic	Protein-tyrosine phosphatase-like	Protein-tyrosine phosphatase, non-receptor type-3, -4	PTPN3/4, FERM domain C-lobe	Tyrosine-specific protein phosphatase, PTPase domain	Tyrosine-specific protein phosphatases domain	Ubiquitin-like domain superfamily
UniProtKB:Q1MTL1 InterPro	930
UniProtKB:F1QFY3 InterPro	935
UniProtKB:A0A8M3B5D0 InterPro	934

Transcripts

Genome Browsers

Type	Name	Annotation Method	Length (nt)	Analysis
mRNA	ptpn4b-201 (1) Ensembl	Ensembl	6,443 nt	Select Tool ZFIN BLAST
mRNA	ptpn4b-202 (1) Ensembl	Ensembl	3,428 nt	Select Tool
mRNA	ptpn4b-203 (1) Ensembl	Ensembl	653 nt	Select Tool

Interactions and Pathways

No data available

Antibodies

No data available

Plasmids

No data available

Constructs

Marker Relationships

Sequences

Orthology

Comparative Orthology: Alliance
Gene Tree: Ensembl

Citations