FIGURE

Fig. 7

ID

ZDB-FIG-120601-53

Publication

Chu et al., 2012 - Overexpression of akt1 enhances adipogenesis and leads to lipoma formation in zebrafish

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Fig. 7

Deregulation of myogenesis-, skeletogenesis-, adipogenesis-, adipocytokine- and inflammation-related genes in Tg(krt4:Hsa.myrAkt1)^cy18.

Comparison of relative expression level of myogenesis/skeletogenesis- (A), adipogenesis- (B), adipocytokine and inflammatory-related (C) gene transcripts between WT and Tg assayed by real-time RT-PCR. Stars labeled above the error bars indicate significant differences as tested by Student’s t-test.*p<0.05, **p<0.01, and ***p<0.001.Visualization of the inflammatory response (red dotted line) in the tail region of both Tg(mpx:GFP)ⁱ¹¹³ (D) and double transgenic progeny derived from Tg(mpx:GFP)ⁱ¹¹³ and Tg(krt4:Hsa.myrAkt1)^cy18 crossing (E).WT, wild type; Tg, Tg(krt4:Hsa.myrAkt1)^cy18.

Expression Data

Genes:	adipoqa adipoqb adipor1a adipor1b adipor2 cebpa col2a1a fabp4a fabp4b il1b lepr lpin1a lpla mgp mmp2 mmp9 myf5 myf6 mylpfa myod1 myog pparg runx2a runx2b scd srebf1 srebf2 tnfa
Fish:	AB cy18Tg
Anatomical Terms:	caudal fin whole organism
Stage:	Adult

Expression Detail

Antibody Labeling

Phenotype Data

Fish:	cy18Tg; i113Tg
Observed In:	post-vent region
Stage:	Adult

Phenotype Detail

Acknowledgments

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