Gene
srebf2
- ID
- ZDB-GENE-070410-8
- Name
- sterol regulatory element binding transcription factor 2
- Symbol
- srebf2 Nomenclature History
- Previous Names
-
- zgc:158371
- Type
- protein_coding_gene
- Location
- Chr: 3 Mapping Details/Browsers
- Description
- Predicted to have DNA-binding transcription factor activity and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Involved in liver development. Predicted to localize to nucleus. Human ortholog(s) of this gene implicated in carotid artery disease; prostate cancer; type 1 diabetes mellitus; type 2 diabetes mellitus; and vascular dementia. Is expressed in liver. Orthologous to human SREBF2 (sterol regulatory element binding transcription factor 2).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 25 figures from 19 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Length | Helix-loop-helix DNA-binding domain superfamily | Myc-type, basic helix-loop-helix (bHLH) domain |
|---|---|---|---|
|
UniProtKB:A3KNA7
|
1099 |
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
srebf2-201
(1)
|
Ensembl | 4,383 nt |
Interactions and Pathways
No data available
Plasmids
No data available