Gene
scd
- ID
- ZDB-GENE-031106-3
- Name
- stearoyl-CoA desaturase (delta-9-desaturase)
- Symbol
- scd Nomenclature History
- Previous Names
-
- SCD1 (1)
- Type
- protein_coding_gene
- Location
- Chr: 12 Mapping Details/Browsers
- Description
- Predicted to enable iron ion binding activity; palmitoyl-CoA 9-desaturase activity; and stearoyl-CoA 9-desaturase activity. Acts upstream of or within fat pad development and swimming behavior. Predicted to be located in membrane. Predicted to be active in endoplasmic reticulum membrane. Is expressed in several structures, including female organism; heart; liver; pleuroperitoneal region; and subcutaneous fat. Human ortholog(s) of this gene implicated in autosomal dominant nonsyndromic deafness 79. Orthologous to human SCD (stearoyl-CoA desaturase) and SCD5 (stearoyl-CoA desaturase 5).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 23 figures from 19 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- 3 figures from Zhang et al., 2022
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
Domain Details Per Protein
Protein | Length | Acyl-CoA desaturase | Fatty acid desaturase domain | Fatty acid desaturase type 1, conserved site |
---|---|---|---|---|
UniProtKB:F1QG70
|
326 |
Interactions and Pathways
No data available
Plasmids
No data available