Fig. 5
- ID
- ZDB-FIG-190611-31
- Publication
- Turner et al., 2019 - Abrogation of Stem Loop Binding Protein (Slbp) function leads to a failure of cells to transition from proliferation to differentiation, retinal coloboma and midline axon guidance deficits
- Other Figures
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slbpty77e mutant cells fail to transition from proliferation to differentiation. (A,A’) DNA content of 48 hpf wildtype and slbpty77e embryos as assessed by flow cytometry. (B,B’, C,C’) Transverse sections through 48hpf wildtype (B,C) and slbpty77emutant (B’,C’) eyes immunostained with anti-BrdU (B,B’) and anti-pH3 antibodies (C,C’). (D,D’) Series of projections of confocal images extracted from live time-lapse movies of tg(EF1α:mAG-zGem(1/100))rw0410h; tg(EF1α: mKO2-zCdt(1/90))rw0405b transgenic wildtype (D) and slbpty77e mutant (D’) embryos showing cell cycle progression in cells of the forming somites. Green cells are proliferative (S, G2, M) whereas red cells are differentiating somite cells. Scale bar: (B-C’) 50μm; (D-D’) 300μm. |
Genes: | |
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Anatomical Terms: | |
Stage Range: | 5-9 somites to Prim-15 |
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Observed In: | |
Stage Range: | 10-13 somites to Long-pec |