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FIGURE 10

Treatment with 2-hydroxypropyl-β-cyclodextrin increased the expression of genes that are related to inflammation and Ca2+ homeostasis in 5 dpf npc2–/– larvae to wildtype levels. Scatterplots show the normalized expression of selected genes in untreated larvae (A) and larvae that were treated with 2 mM 2HPβCD (B) at 5 dpf. Each circle corresponds to one zebrafish. The 18S ribosomal gene was used as a reference. The experiments were performed in triplicate. ***p < 0.001, **p < 0.01, *p < 0.05.

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