Gene
mpeg1.1
- ID
- ZDB-GENE-030131-7347
- Name
- macrophage expressed 1, tandem duplicate 1
- Symbol
- mpeg1.1 Nomenclature History
- Previous Names
-
- mpeg1
- fj09e08
- wu:fb14d06
- wu:fj09e08
- zgc:66409
- Type
- protein_coding_gene
- Location
- Chr: 8 Mapping Details/Browsers
- Description
- Acts upstream of or within defense response to bacterium. Predicted to be located in cytoplasmic vesicle membrane. Is expressed in several structures, including blood island; digestive system; endothelial cell; immune system; and reproductive system. Human ortholog(s) of this gene implicated in primary immunodeficiency disease. Orthologous to human MPEG1 (macrophage expressed 1).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 65 figures from 46 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- MGC:66409 (5 images)
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| Immunodeficiency 77 | 619223 |
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Length | Macrophage-expressed gene 1 protein | Membrane attack complex component/perforin (MACPF) domain |
|---|---|---|---|
|
UniProtKB:Q7SXE0
|
718 |
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
mpeg1.1-201
(1)
|
Ensembl | 2,634 nt | ||
| mRNA |
mpeg1.1-202
(1)
|
Ensembl | 820 nt |
Interactions and Pathways
No data available
Plasmids