FIGURE

Fig. 5

ID

ZDB-FIG-240313-19

Publication

Auman et al., 2023 - Zebrafish smarcc1a mutants reveal requirements for BAF chromatin remodeling complexes in distinguishing the atrioventricular canal from the cardiac chambers

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Fig. 5

Cardiac chamber identity is established normally in the smarcc1a mutant heart tube. (A–L) Whole-mount in situ hybridization compares expression of myl7 in all cardiomyocytes (A, D, G, J) with expression of vmhc in ventricular cardiomyocytes (B, E, H, K) and amhc in atrial cardiomyocytes (C, F, I, L). (A–F) Dorsal views at 30 hpf, ventricle to the top. (G–L) Frontal views at 48 hpf, ventricle to the top. vmhc and amhc expression are found in complementary domains corresponding to ventricular and atrial identities in both wild-type embryos and smarcc1a mutants within the linear heart tube (A–F) and as development proceeds (G–L).

Expression Data

Genes:	myh6 myh7 myl7
Fish:	smarcc1a^sk29/sk29
Anatomical Terms:	atrium cardiac muscle cell cardiac ventricle cardiac muscle cell heart heart tube presumptive atrium heart tube cardiac muscle cell presumptive cardiac ventricle heart tube cardiac muscle cell
Stage Range:	Prim-15 to Long-pec

Expression Detail

Antibody Labeling

Phenotype Data

Fish:	smarcc1a^sk29/sk29
Observed In:	heart
Stage:	Long-pec

Phenotype Detail

Acknowledgments

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