FIGURE

Fig. 5

ID

ZDB-FIG-210504-20

Publication

Peng et al., 2020 - Induction of Wnt signaling antagonists and p21-activated kinase enhances cardiomyocyte proliferation during zebrafish heart regeneration

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Fig. 5

Inhibiting Pak2 activity using dominant-negative mutation or chemical inhibitor reduces pS675-?-catenin at wound edges in the regenerating heart. (A?D) Immunostaining and ISH analyses displaying increased Pak2 and pak2a expression, respectively, at wounded myocardial cell edge in injured hearts at 3 dpa (B and D) compared to uninjured heart (A and C). Scale bar, 100 �m. (E) qPCR analysis for expression levels of pak1, pak2a, and pak2b in uninjured and resected WT hearts at 3 or 7 dpa. ?-actin expression was used for normalization. Data are mean � SEM from three biological replicates and three technical replicates. Student?s t-test, **P?

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image. Full text @ J. Mol. Cell Biol.