ZFIN Image: Peng et al., 2020, Fig. 5

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Figure Caption

Fig. 5 Inhibiting Pak2 activity using dominant-negative mutation or chemical inhibitor reduces pS675-?-catenin at wound edges in the regenerating heart. (A?D) Immunostaining and ISH analyses displaying increased Pak2 and pak2a expression, respectively, at wounded myocardial cell edge in injured hearts at 3 dpa (B and D) compared to uninjured heart (A and C). Scale bar, 100 �m. (E) qPCR analysis for expression levels of pak1, pak2a, and pak2b in uninjured and resected WT hearts at 3 or 7 dpa. ?-actin expression was used for normalization. Data are mean � SEM from three biological replicates and three technical replicates. Student?s t-test, **P?

Acknowledgments

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