FIGURE

Fig. 4

ID

ZDB-FIG-200207-4

Publication

Tian et al., 2020 - Systemic loss of Sarm1 protects Schwann cells from chemotoxicity by delaying axon degeneration

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Fig. 4

Sarm1 is necessary for late onset axoplasmic Ca<sup>2+</sup> influx in severed axons.

a Confocal image of a lateralis sensory axons expressing the mCherry (red) and green-fluorescent calcium sensor GCaMP7a (green) in wild-type fish. Rows show same axons 2, 4, 8, and 12 h after transection (hours post-injury = hpi). b Confocal image of lateralis sensory axons expressing the mCherry (red) and green-fluorescent calcium sensor GCaMP7a (green) in Sarm1−/− fish. Scale bar 20 μm.

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Fish:	sarm1^hzm13/hzm13; bc3Tg
Condition:	transection: axon: posterior lateral line nerve
Observed In:	lateral line nerve calcium ion import
Stage:	Day 5

Phenotype Detail

Acknowledgments

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