FIGURE

Fig 1

ID

ZDB-FIG-200206-1

Publication

Hin et al., 2020 - Accelerated brain aging towards transcriptional inversion in a zebrafish model of the K115fs mutation of human PSEN2

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Fig 1

Quantification of heterozygous mutant and wild type allele relative transcript expression.

Digital quantitative PCRs specifically detecting transcripts from the heterozygous mutant (K97fs) or wild type (+) alleles of psen1 were performed using cDNA synthesised from total brain mRNA from fish at 6 and 24 months of age. Means and standard error of the means are indicated, and p-values are from two-sample t-tests assuming unequal variances.

Expression Data

Gene:	psen1
Fish:	TU psen1^uaa10/+
Anatomical Term:	female organism brain
Stage:	Adult

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

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