FIGURE

Fig. S6

ID

ZDB-FIG-180529-39

Publication

Naharros et al., 2018 - The ciliopathy protein TALPID3/KIAA0586 acts upstream of Rab8 activation in zebrafish photoreceptor outer segment formation and maintenance

Other Figures

All Figure Page

Back to All Figure Page

Fig. S6

Rescue of OS development by expression of constitutively active Rab8a in rod PRs

(A) Cryosection of 4 dpf zebrafish ta3-/- larva expressing constitutively active Rab8a in rod PRs (rhod:mCherry-Rab8aCA, red) and stained with DiO (green) to highlight membranes and OSs. Rod PRs expressing Rab8aCA develop OSs. (B) is a close-up image of the inset in (A). (B') shows only the red channel (Rab8aCA) and (B'') shows the green channel highlighting the presence of the OS. Scale bars are 4 μm in A and 2 μm in B-B''. (C) Quantification of OS development in rod PRs expressing Rab8aCA. Each red datapoint (circles) represents the percentage of PRs expressing the transgene that developed an OS in a single larva, while each green datapoint (squares) indicates the percentage of rod PRs ot expressing the transgene that developed OSs.

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image. Full text @ Sci. Rep.