FIGURE

Fig. S2

ID

ZDB-FIG-180529-35

Publication

Naharros et al., 2018 - The ciliopathy protein TALPID3/KIAA0586 acts upstream of Rab8 activation in zebrafish photoreceptor outer segment formation and maintenance

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Fig. S2

Time course of PR degeneration in ta3 mutants

Retinal cryosections of wt and ta3-/- zebrafish at 3dpf (A-B'), 4dpf (C-D'), 5dpf (E-F') and 6 dpf (G-H'). Nuclei are counterstained with DAPI and membranes (including outer segments) are highlighted with BODIPY. Note the progressive cell shape loss and decreased numbers of outer segments in mutants. The arrow in H' indicates a PR with an OS, while the arrowheads point to PRs without OSs. (I-J) Histological sections through whole wt and ta3-/- eyes at 6dpf showing gaps in the PR cell layer, but also persistance of many PR cells. Scale bars: 30 μm in (A-H) and (I-J), 4 μm in A'-H'.

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

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