ZFIN Image: Naharros et al., 2018, Fig. S6

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Figure Caption

Fig. S6

Rescue of OS development by expression of constitutively active Rab8a in rod PRs

(A) Cryosection of 4 dpf zebrafish ta3-/- larva expressing constitutively active Rab8a in rod PRs (rhod:mCherry-Rab8aCA, red) and stained with DiO (green) to highlight membranes and OSs. Rod PRs expressing Rab8aCA develop OSs. (B) is a close-up image of the inset in (A). (B') shows only the red channel (Rab8aCA) and (B'') shows the green channel highlighting the presence of the OS. Scale bars are 4 μm in A and 2 μm in B-B''. (C) Quantification of OS development in rod PRs expressing Rab8aCA. Each red datapoint (circles) represents the percentage of PRs expressing the transgene that developed an OS in a single larva, while each green datapoint (squares) indicates the percentage of rod PRs ot expressing the transgene that developed OSs.

Acknowledgments

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