FIGURE

Fig. S12

ID

ZDB-FIG-141007-54

Publication

Bielczyk-Maczyńska et al., 2014 - A loss of function screen of identified genome-wide association study Loci reveals new genes controlling hematopoiesis

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Fig. S12

In order to assess vascular development, MOs targeting candidate genes were injected into Tg(fli1:EGFP) embryos. Vascular morphology of the embryos was assessed at 3 dpf. No major abnormalities in vascular morphogenesis were observed for any of the tested MOs, indicating that the hematopoietic defects were not secondary to a vascular phenotype. Representative images of the CHT region are shown. All embryos are oriented with anterior to the left and dorsal to the top.

Expression Data

Gene:	EGFP
Fish:	y1Tg y1Tg + MO1-akap10 y1Tg + MO1-brd3a y1Tg + MO1-brf1a y1Tg + MO1-brf1b y1Tg + MO1-cfap251 y1Tg + MO1-kalrna y1Tg + MO1-kalrnb y1Tg + MO1-pdia5 y1Tg + MO1-psmd13 y1Tg + MO1-satb1b y1Tg + MO1-wasla y1Tg + MO1-waslb y1Tg + MO2-mfn2 y1Tg + MO2-rcor1 y1Tg + MO4-kif1b
Knockdown Reagents:	MO1-akap10 MO1-brd3a MO1-brf1a MO1-brf1b MO1-cfap251 MO1-kalrna MO1-kalrnb MO1-pdia5 MO1-psmd13 MO1-satb1b MO1-wasla MO1-waslb MO2-mfn2 MO2-rcor1 MO4-kif1b
Anatomical Terms:	endothelial cell intersegmental vessel trunk vasculature unspecified
Stage:	Protruding-mouth

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

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