FIGURE

Fig. 3

ID

ZDB-FIG-110622-26

Publication

Waxman et al., 2011 - Zebrafish retinoic acid receptors function as context-dependent transcriptional activators

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Fig. 3

Ectopic expression of zebrafish RARs does not sensitize embryos to RA signaling. (A) Schematic composition of RAR constructs used in experiments. (B) Uninjected Tg(12XRARE-ef1a:gfp) embryo. (C, D) Tg(12XRARE-ef1a:gfp) embryos injected with zebrafish rarab (C) or rarga (D) mRNA appear normal, and reporter expression is unaffected. (E) Tg(12XRARE-ef1a:gfp) embryo continuously treated with 0.05 μM RA. (F, G) Tg(12XRARE-ef1a:gfp) embryo injected with zebrafish rarab (F) or rarga (G) mRNA and treated with 0.05 μM RA are not more affected than uninjected embryos. All images are lateral views, with anterior up and dorsal to the right.

Expression Data

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Antibody Labeling

Phenotype Data

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Acknowledgments

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Reprinted from Developmental Biology, 352(1), Waxman, J.S., and Yelon, D., Zebrafish retinoic acid receptors function as context-dependent transcriptional activators, 128-140, Copyright (2011) with permission from Elsevier. Full text @ Dev. Biol.