FIGURE

Fig. 1

ID

ZDB-FIG-110322-54

Publication

van der Velden et al., 2011 - The serine-threonine kinase LKB1 is essential for survival under energetic stress in zebrafish

Other Figures

All Figure Page

Back to All Figure Page

Fig. 1

Characterization of zebrafish lkb1 mutations. (A) Whole-mount in situ hybridizations show decreased lkb1 mRNA expression in 3-dpf lkb1-mutant larvae. (B) Western blot analysis of AMPK and ACC upon KCN treatment. KCN treatment results in activation of the AMPK pathway in 3-dpf WT larvae but not in 3-dpf lkb1-mutant larvae.

Expression Data

Gene:	stk11
Fish:	WT stk11^{hu1960/hu1960} stk11^{hu1968/hu1968}
Anatomical Term:	head
Stage:	Protruding-mouth

Expression Detail

Antibody Labeling

Phenotype Data

Fish:	stk11^{hu1960/hu1960} stk11^{hu1968/hu1968}
Observed In:	protein phosphorylation
Stage:	Protruding-mouth

Phenotype Detail

Acknowledgments

This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image. Full text @ Proc. Natl. Acad. Sci. USA