FIGURE

Fig. 13

ID

ZDB-FIG-090617-42

Publication

Bae et al., 2009 - Anatomy of zebrafish cerebellum and screen for mutations affecting its development

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Fig. 13

Cerebellar mutants. (A–E) Wild-type, (F–J) evanescence (eva), (K–O) asynergy (asy), (P–T) gazami (gaz), and (U–Y) shiomaneki (sio) mutant larvae at 5 dpf. The embryos and larvae were treated with phenylthiourea to prevent pigmentation. The fixed 5-dpf larvae were stained with anti-Pvalb7 and Vglut1 antibodies. Bright-field images of the entire body (A, F, K, P, U) and the head region (B, G, L, Q, V). Lateral views with anterior to the left. Pvalb7 immunostaining (green; C, H, M, R, W), Vglut1 immunostaining (magenta; D, I, N, S, X), and merged images (E, J, O, T, Y). Dorsal views with anterior to the left. The eva and asy mutants had small eyes (indicated by arrows). Scale bars: 1 mm (U) and 200 μm (V, Y).

Expression Data

Genes:	pvalb7 slc17a7a
Antibody:	Ab1-slc17a7
Fish:	WT asy^rk12/rk12 cfdp1^rk17/rk17 chm^rk10/rk10 col4a6^rk18/rk18
Anatomical Terms:	corpus cerebelli Purkinje cell granule cell axon molecular layer corpus cerebelli
Stage:	Day 5

Expression Detail

Antibody Labeling

Phenotype Data

Fish:	asy^rk12/rk12 asy^rk13/rk13 cfdp1^rk17/rk17 chm^rk10/rk10 col4a6^rk18/rk18
Observed In:	cerebellum granule cell cerebellum Purkinje cell eye granule cell axon head molecular layer corpus cerebelli post-vent region
Stage:	Day 5

Phenotype Detail

Acknowledgments

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Reprinted from Developmental Biology, 330(2), Bae, Y.K., Kani, S., Shimizu, T., Tanabe, K., Nojima, H., Kimura, Y., Higashijima, S.I., and Hibi, M., Anatomy of zebrafish cerebellum and screen for mutations affecting its development, 406-426, Copyright (2009) with permission from Elsevier. Full text @ Dev. Biol.