FIGURE

Fig. 8

ID

ZDB-FIG-060823-11

Publication

Walker et al., 2006 - Zebrafish furin mutants reveal intricacies in regulating Endothelin1 signaling in craniofacial patterning

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Fig. 8

Intermediate arch domains are misspecified in furinA mutants. (A, B) bapx1 expression is strongly reduced in furinA mutants at 48 hpf. (C, D) At 45 hpf, gsc is ectopically expressed in a second arch intermediate domain in furinA mutants. (E, F) barx1 is ectopically expressed in a second arch intermediate domain in furinA mutants at 48 hpf. (G, H) sox9a is ectopically expressed in a second arch intermediate domain in furinA mutants at 48 hpf. (I, J) runx2b is ectopically expressed in a second arch intermediate domain in furinA mutants at 55 hpf. Arrows indicate a second arch intermediate domain in wild-type embryos. Asterisks indicate ectopic expression in a second arch intermediate domain in furinA mutant embryos. a1 and a2 label pharyngeal arch 1 and 2. Scale bars: 50 μm.

Expression Data

Genes:	barx1 gsc nkx3-2 runx2b sox9a
Fish:	WT furina^tg419/tg419
Anatomical Term:	pharyngeal arch
Stage Range:	High-pec to Long-pec

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

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Reprinted from Developmental Biology, 295(1), Walker, M.B., Miller, C.T., Talbot, J.C., Stock, D.W., and Kimmel, C.B., Zebrafish furin mutants reveal intricacies in regulating Endothelin1 signaling in craniofacial patterning, 194-205, Copyright (2006) with permission from Elsevier. Full text @ Dev. Biol.