Gene
nkx3-2
- ID
- ZDB-GENE-030127-1
- Name
- NK3 homeobox 2
- Symbol
- nkx3-2 Nomenclature History
- Previous Names
- Type
- protein_coding_gene
- Location
- Chr: 14 Mapping Details/Browsers
- Description
- Predicted to have DNA-binding transcription factor activity and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Involved in embryonic viscerocranium morphogenesis. Predicted to localize to nucleus. Is expressed in several structures, including neuromast; notochord; pharyngeal arch; pharyngeal endoderm; and skeletal system. Orthologous to human NKX3-2 (NK3 homeobox 2).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 43 figures from 30 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- eu470 (13 images)
Wild Type Expression Summary
- All Phenotype Data
- 22 figures from 5 publications
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| Spondylo-megaepiphyseal-metaphyseal dysplasia | 613330 |
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Length | Homedomain-like superfamily | Homeobox, conserved site | Homeobox NK-like transcription regulators | Homeodomain | Homeodomain, metazoa |
|---|---|---|---|---|---|---|
|
UniProtKB:Q803Z6
|
245 |
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
nkx3.2-201
(1)
|
Ensembl | 1,964 nt |
Interactions and Pathways
No data available
Plasmids
No data available