Gene

gsc

ID

ZDB-GENE-980528-2060

Name

goosecoid

Symbol

gsc Nomenclature History

Previous Names

etID102410.17 (1)
etID5964.17 (1)
ik:tdsubc_1c10 (1)
ik:tdsubc_2g4 (1)
ik:tdsubc_2h11
xx:tdsubc_1c10
xx:tdsubc_2g4
xx:tdsubc_2h11
zgc:101595
ZGSC

Type

protein_coding_gene

Location

Chr: 17 Mapping Details/Browsers

Description

Predicted to have sequence-specific DNA binding activity. Involved in several processes, including neuroblast delamination; otic vesicle development; and regionalization. Predicted to localize to nucleus. Is expressed in several structures, including blastodisc; germ ring; mesoderm; neural keel; and pharyngeal arch. Orthologous to human GSC (goosecoid homeobox).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

396 figures from 295 publications

Cross-Species Comparison

High Throughput Data

GEO (1)

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Daniocell

Thisse Expression Data

MGC:101595 (68 images)
eu565 (1 image)

Wild Type Expression Summary

Phenotype

All Phenotype Data: 5 figures from 2 publications
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With gsc Human Ortholog

Disease Ontology Term	Multi-Species Data	OMIM Term	OMIM Phenotype ID
		Short stature, auditory canal atresia, mandibular hypoplasia, skeletal abnormalities	602471

Associated With gsc Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Conserved_site	IPR017970	Homeobox, conserved site
Domain	IPR001356	Homeodomain
Family	IPR051440	Goosecoid-like homeobox
Homologous_superfamily	IPR009057	Homedomain-like superfamily