Morpholino

MO1-septin15

ID
ZDB-MRPHLNO-140606-7
Name
MO1-septin15
Previous Names
  • MO1-sept15
  • TBMO (1)
Target
Sequence
5' - TCGGGTCTCTCGATCATTGTCCTGT - 3'
ZFIN BLAST NCBI BLAST Ensembl UCSC BLAT
Disclaimer
Although ZFIN verifies reagent sequence data, we recommend that you conduct independent sequence analysis before ordering any reagent.
Note
Translation-blocking MO.
Genome Resources
None
Target Location
Genomic Features
No data available
Expression
Gene expression in Wild Types + MO1-septin15
Expressed Gene Anatomy Figures
aldh1a2 Fig. 7 from Dash et al., 2017
ascl1b Fig. 6 with image from Dash et al., 2016
ins Fig. 2 with image,  Fig. 3 with image,  Fig. 4 with image,  Fig. 7 with image,  Fig. 8 with image from Dash et al., 2016
myl7 Fig. 7 with image from Dash et al., 2014
notch1a Fig. 6 with image from Dash et al., 2016
notch1b Fig. 6 with image from Dash et al., 2016
pck1 Fig. 8 with image from Dash et al., 2016
pdx1 Fig. 5 with image from Dash et al., 2016
prss1 Fig. 4 with image from Dash et al., 2016
septin15 Fig. 2 from Dash et al., 2017
Fig. 2 with image from Dash et al., 2014
shha Fig. 6 with image from Dash et al., 2016
spaw Fig. 7 with image from Dash et al., 2014
Phenotype
Phenotype resulting from MO1-septin15
Phenotype Fish Figures
atrium elongated, abnormal WT + MO1-septin15 Fig. 2 from Dash et al., 2017
brain hydrocephalic, abnormal WT + MO1-septin15 Fig. 7 with image from Dash et al., 2014
cardiac ventricle septin15 expression absent, abnormal WT + MO1-septin15 Fig. 2 from Dash et al., 2017
cardiac ventricle decreased size, abnormal WT + MO1-septin15 Fig. 2,  Fig. 5 from Dash et al., 2017
central canal has fewer parts of type ependymal cell cilium, abnormal WT + MO1-septin15 Fig. 7 with image from Dash et al., 2014
cilium assembly decreased process quality, abnormal li1Tg + MO1-septin15 Fig. 5 with image from Dash et al., 2014
embryonic heart tube left/right pattern formation decreased process quality, abnormal WT + MO1-septin15 Fig. 7 with image from Dash et al., 2014
endocrine pancreas has fewer parts of type pancreatic A cell, abnormal ia1Tg + MO1-septin15 Fig. 3 with image from Dash et al., 2016
endocrine pancreas has fewer parts of type pancreatic B cell, abnormal WT + MO1-septin15 Fig. 2 with image from Dash et al., 2016
endocrine pancreas development decreased process quality, abnormal nl1Tg + MO1-septin15 Fig. 7 with image from Dash et al., 2016
endoderm shha expression absent, abnormal WT + MO1-septin15 Fig. 6 with image from Dash et al., 2016
ependymal cell cilium decreased length, abnormal WT + MO1-septin15 Fig. 7 with image from Dash et al., 2014
ependymal cell cilium disoriented, abnormal WT + MO1-septin15 Fig. 7 with image from Dash et al., 2014
exocrine pancreas decreased length, abnormal WT + MO1-septin15 Fig. 4 with image from Dash et al., 2016
exocrine pancreas malformed, abnormal jh1Tg + MO1-septin15 Fig. 4 with image from Dash et al., 2016
exocrine pancreas EGFP expression mislocalised, abnormal nl1Tg + MO1-septin15 Fig. 7 with image from Dash et al., 2016
exocrine pancreas development decreased process quality, abnormal jh1Tg + MO1-septin15 Fig. 4 with image from Dash et al., 2016
glomerular filtration decreased process quality, abnormal WT + MO1-septin15 Fig. 4 with image from Dash et al., 2014
gut epithelium EGFP expression mislocalised, abnormal nl1Tg + MO1-septin15 Fig. 7 with image from Dash et al., 2016
gut epithelium ins expression mislocalised, abnormal nl1Tg + MO1-septin15 Fig. 7 with image from Dash et al., 2016
heart septin15 expression absent, abnormal WT + MO1-septin15 Fig. 2 from Dash et al., 2017
heart aldh1a2 expression decreased amount, abnormal WT + MO1-septin15 Fig. 7 from Dash et al., 2017
heart edematous, abnormal WT + MO1-septin15 Fig. 2 with image from Dash et al., 2014
heart morphology, abnormal WT + MO1-septin15 Fig. 2 from Dash et al., 2017
heart cardiac myofibril disorganized, abnormal WT + MO1-septin15 Fig. 2,  Fig. 3 from Dash et al., 2017
heart striated muscle myosin thick filament disorganized, abnormal WT + MO1-septin15 Fig. 2 from Dash et al., 2017
heart striated muscle thin filament Ab2-actc1 labeling decreased amount, abnormal WT + MO1-septin15 Fig. 4 from Dash et al., 2017
heart striated muscle thin filament disorganized, abnormal WT + MO1-septin15 Fig. 2 from Dash et al., 2017
heart Z disc absent, abnormal WT + MO1-septin15 Fig. 3 from Dash et al., 2017
heart Z disc disorganized, abnormal WT + MO1-septin15 Fig. 3 from Dash et al., 2017
heart Z disc structure, abnormal WT + MO1-septin15 Fig. 3 from Dash et al., 2017
heart contraction decreased process quality, abnormal WT + MO1-septin15 Fig. 5,  Fig. 7 from Dash et al., 2017
heart contraction decreased rate, abnormal WT + MO1-septin15 Fig. 5 from Dash et al., 2017
heart contraction process quality, abnormal WT + MO1-septin15 Fig. 7 from Dash et al., 2017
heart looping decreased occurrence, abnormal WT + MO1-septin15 Fig. 2,  Fig. 5 from Dash et al., 2017
heart tube bilateral symmetry, abnormal WT + MO1-septin15 Fig. 7 with image from Dash et al., 2014
intrapancreatic duct ins expression mislocalised, abnormal nl1Tg + MO1-septin15 Fig. 7 with image from Dash et al., 2016
intrapancreatic duct EGFP expression mislocalised, abnormal nl1Tg + MO1-septin15 Fig. 7 with image from Dash et al., 2016
islet cell differentiation decreased process quality, abnormal jh1Tg + MO1-septin15 Fig. 5 with image from Dash et al., 2016
Kupffer's vesicle motile cilium decreased length, abnormal WT + MO1-septin15 Fig. 5 with image from Dash et al., 2014
lateral plate mesoderm bilateral symmetry, abnormal WT + MO1-septin15 Fig. 7 with image from Dash et al., 2014
muscle muscle tendon junction septin15 expression absent, abnormal WT + MO1-septin15 Fig. 2 from Dash et al., 2017
pancreas pancreatic A cell differentiation decreased occurrence, abnormal ia1Tg + MO1-septin15 Fig. 3 with image from Dash et al., 2016
pancreatic B cell cell population proliferation decreased occurrence, abnormal WT + MO1-septin15 Fig. 2 with image from Dash et al., 2016
post-vent region curved, abnormal WT + MO1-septin15 Fig. 2 with image from Dash et al., 2014
pronephric capsular space dilated, abnormal WT + MO1-septin15 Fig. 2 with image from Dash et al., 2014
pronephric podocyte lacks parts or has fewer parts of type pronephric podocyte slit diaphragm, abnormal WT + MO1-septin15 Fig. 3 with image from Dash et al., 2014
pronephric podocyte apical part of cell malformed, abnormal WT + MO1-septin15 Fig. 3 with image from Dash et al., 2014
pronephric podocyte cell projection malformed, abnormal WT + MO1-septin15 Fig. 3 with image from Dash et al., 2014
pronephric tubule dilated, abnormal WT + MO1-septin15 Fig. 2 with image,  Fig. 3 with image from Dash et al., 2014
pronephric tubule has fewer parts of type pronephric tubule microvillus, abnormal WT + MO1-septin15 Fig. 3 with image from Dash et al., 2014
pronephric tubule increased diameter, abnormal WT + MO1-septin15 Fig. 5 with image from Dash et al., 2014
pronephric tubule actin cytoskeleton decreased object quality, abnormal WT + MO1-septin15 Fig. 6 with image from Dash et al., 2014
pronephric tubule apical part of cell physical object quality, abnormal WT + MO1-septin15 Fig. 6 with image from Dash et al., 2014
pronephric tubule ciliary basal body disorganized, abnormal WT + MO1-septin15 Fig. 5 with image from Dash et al., 2014
pronephric tubule motile cilium decreased length, abnormal li1Tg + MO1-septin15 Fig. 5 with image from Dash et al., 2014
pronephric tubule motile cilium disoriented, abnormal WT + MO1-septin15 Fig. 5 with image from Dash et al., 2014
pronephros cystic, abnormal WT + MO1-septin15 Fig. 2 with image from Dash et al., 2014
pronephros morphogenesis decreased process quality, abnormal WT + MO1-septin15 Fig. 2 with image,  Fig. 3 with image from Dash et al., 2014
renal water transport decreased process quality, abnormal WT + MO1-septin15 Fig. 4 with image from Dash et al., 2014
whole organism notch1b expression decreased amount, abnormal WT + MO1-septin15 Fig. 6 with image from Dash et al., 2016
whole organism notch1a expression decreased amount, abnormal WT + MO1-septin15 Fig. 6 with image from Dash et al., 2016
whole organism ins expression decreased amount, abnormal WT + MO1-septin15 Fig. 8 with image from Dash et al., 2016
whole organism ascl1b expression increased amount, abnormal WT + MO1-septin15 Fig. 6 with image from Dash et al., 2016
whole organism pck1 expression increased amount, abnormal WT + MO1-septin15 Fig. 8 with image from Dash et al., 2016
whole organism anterior region aldh1a2 expression decreased amount, abnormal WT + MO1-septin15 Fig. 7 from Dash et al., 2017
whole organism glucose increased amount, abnormal WT + MO1-septin15 Fig. 8 with image from Dash et al., 2016
whole organism glucose homeostasis decreased process quality, abnormal WT + MO1-septin15 Fig. 8 with image from Dash et al., 2016
yolk edematous, abnormal WT + MO1-septin15 Fig. 2 with image from Dash et al., 2014
Phenotype of all Fish created by or utilizing MO1-septin15
Phenotype Fish Conditions Figures
cardiac ventricle septin15 expression absent, abnormal WT + MO1-septin15 standard conditions Fig. 2 from Dash et al., 2017
pronephros morphogenesis decreased process quality, abnormal WT + MO1-septin15 standard conditions Fig. 2 with image,  Fig. 3 with image from Dash et al., 2014
muscle muscle tendon junction septin15 expression absent, abnormal WT + MO1-septin15 standard conditions Fig. 2 from Dash et al., 2017
lateral plate mesoderm bilateral symmetry, abnormal WT + MO1-septin15 standard conditions Fig. 7 with image from Dash et al., 2014
cilium assembly decreased process quality, abnormal WT + MO1-septin15 standard conditions Fig. 5 with image from Dash et al., 2014
pronephric tubule ciliary basal body disorganized, abnormal WT + MO1-septin15 standard conditions Fig. 5 with image from Dash et al., 2014
heart contraction decreased rate, abnormal WT + MO1-septin15 standard conditions Fig. 5 from Dash et al., 2017
whole organism pck1 expression increased amount, abnormal WT + MO1-septin15 control Fig. 8 with image from Dash et al., 2016
whole organism ascl1b expression increased amount, abnormal WT + MO1-septin15 standard conditions Fig. 6 with image from Dash et al., 2016
heart contraction decreased process quality, abnormal WT + MO1-septin15 standard conditions Fig. 5,  Fig. 7 from Dash et al., 2017
heart striated muscle thin filament Ab2-actc1 labeling decreased amount, abnormal WT + MO1-septin15 standard conditions Fig. 4 from Dash et al., 2017
embryonic heart tube left/right pattern formation decreased process quality, abnormal WT + MO1-septin15 standard conditions Fig. 7 with image from Dash et al., 2014
whole organism glucose homeostasis decreased process quality, abnormal WT + MO1-septin15 standard conditions Fig. 8 with image from Dash et al., 2016
pronephric tubule motile cilium disoriented, abnormal WT + MO1-septin15 standard conditions Fig. 5 with image from Dash et al., 2014
pronephric podocyte lacks parts or has fewer parts of type pronephric podocyte slit diaphragm, abnormal WT + MO1-septin15 standard conditions Fig. 3 with image from Dash et al., 2014
Kupffer's vesicle motile cilium decreased length, abnormal WT + MO1-septin15 standard conditions Fig. 5 with image from Dash et al., 2014
pronephric capsular space dilated, abnormal WT + MO1-septin15 standard conditions Fig. 2 with image from Dash et al., 2014
endoderm shha expression absent, abnormal WT + MO1-septin15 standard conditions Fig. 6 with image from Dash et al., 2016
pronephros cystic, abnormal WT + MO1-septin15 standard conditions Fig. 2 with image from Dash et al., 2014
heart contraction decreased process quality, abnormal WT + MO1-septin15 chemical treatment: 4-(diethylamino)benzaldehyde Fig. 8 from Dash et al., 2017
ependymal cell cilium disoriented, abnormal WT + MO1-septin15 standard conditions Fig. 7 with image from Dash et al., 2014
heart Z disc structure, abnormal WT + MO1-septin15 standard conditions Fig. 3 from Dash et al., 2017
whole organism glucose increased amount, abnormal WT + MO1-septin15 standard conditions Fig. 8 with image from Dash et al., 2016
heart tube bilateral symmetry, abnormal WT + MO1-septin15 standard conditions Fig. 7 with image from Dash et al., 2014
heart striated muscle thin filament disorganized, abnormal WT + MO1-septin15 standard conditions Fig. 2 from Dash et al., 2017
exocrine pancreas decreased length, abnormal WT + MO1-septin15 standard conditions Fig. 4 with image from Dash et al., 2016
pronephric tubule apical part of cell physical object quality, abnormal WT + MO1-septin15 standard conditions Fig. 6 with image from Dash et al., 2014
pronephric podocyte apical part of cell malformed, abnormal WT + MO1-septin15 standard conditions Fig. 3 with image from Dash et al., 2014
renal water transport decreased process quality, abnormal WT + MO1-septin15 standard conditions Fig. 4 with image from Dash et al., 2014
glomerular filtration decreased process quality, abnormal WT + MO1-septin15 standard conditions Fig. 4 with image from Dash et al., 2014
post-vent region curved, abnormal WT + MO1-septin15 standard conditions Fig. 2 with image from Dash et al., 2014
whole organism ins expression decreased amount, abnormal WT + MO1-septin15 chemical treatment by environment: glucose Fig. 8 with image from Dash et al., 2016
heart contraction process quality, abnormal WT + MO1-septin15 chemical treatment: retinoic acid Fig. 7 from Dash et al., 2017
pronephric tubule actin cytoskeleton decreased object quality, abnormal WT + MO1-septin15 standard conditions Fig. 6 with image from Dash et al., 2014
heart septin15 expression absent, abnormal WT + MO1-septin15 standard conditions Fig. 2 from Dash et al., 2017
cardiac ventricle decreased size, abnormal WT + MO1-septin15 standard conditions Fig. 2,  Fig. 5 from Dash et al., 2017
whole organism notch1b expression decreased amount, abnormal WT + MO1-septin15 standard conditions Fig. 6 with image from Dash et al., 2016
brain hydrocephalic, abnormal WT + MO1-septin15 standard conditions Fig. 7 with image from Dash et al., 2014
ependymal cell cilium decreased length, abnormal WT + MO1-septin15 standard conditions Fig. 7 with image from Dash et al., 2014
heart aldh1a2 expression decreased amount, abnormal WT + MO1-septin15 standard conditions Fig. 7 from Dash et al., 2017
whole organism pck1 expression increased amount, abnormal WT + MO1-septin15 chemical treatment by environment: glucose Fig. 8 with image from Dash et al., 2016
heart striated muscle myosin thick filament disorganized, abnormal WT + MO1-septin15 standard conditions Fig. 2 from Dash et al., 2017
heart contraction process quality, abnormal WT + MO1-septin15 control Fig. 7 from Dash et al., 2017
heart edematous, abnormal WT + MO1-septin15 standard conditions Fig. 2 with image from Dash et al., 2014
heart morphology, abnormal WT + MO1-septin15 standard conditions Fig. 2 from Dash et al., 2017
pancreatic B cell cell population proliferation decreased occurrence, abnormal WT + MO1-septin15 control Fig. 2 with image from Dash et al., 2016
central canal has fewer parts of type ependymal cell cilium, abnormal WT + MO1-septin15 standard conditions Fig. 7 with image from Dash et al., 2014
whole organism anterior region aldh1a2 expression decreased amount, abnormal WT + MO1-septin15 standard conditions Fig. 7 from Dash et al., 2017
whole organism glucose homeostasis decreased process quality, abnormal WT + MO1-septin15 chemical treatment by environment: glucose Fig. 8 with image from Dash et al., 2016
heart looping decreased occurrence, abnormal WT + MO1-septin15 standard conditions Fig. 2,  Fig. 5 from Dash et al., 2017
pronephric podocyte cell projection malformed, abnormal WT + MO1-septin15 standard conditions Fig. 3 with image from Dash et al., 2014
heart contraction increased process quality, abnormal WT + MO1-septin15 chemical treatment: retinoic acid Fig. 7 from Dash et al., 2017
endocrine pancreas has fewer parts of type pancreatic B cell, abnormal WT + MO1-septin15 control Fig. 2 with image from Dash et al., 2016
pronephric tubule dilated, abnormal WT + MO1-septin15 standard conditions Fig. 2 with image,  Fig. 3 with image from Dash et al., 2014
whole organism notch1a expression decreased amount, abnormal WT + MO1-septin15 standard conditions Fig. 6 with image from Dash et al., 2016
heart cardiac myofibril disorganized, abnormal WT + MO1-septin15 standard conditions Fig. 2,  Fig. 3 from Dash et al., 2017
pronephric tubule increased diameter, abnormal WT + MO1-septin15 standard conditions Fig. 5 with image from Dash et al., 2014
heart Z disc absent, abnormal WT + MO1-septin15 standard conditions Fig. 3 from Dash et al., 2017
pronephric tubule has fewer parts of type pronephric tubule microvillus, abnormal WT + MO1-septin15 standard conditions Fig. 3 with image from Dash et al., 2014
yolk edematous, abnormal WT + MO1-septin15 standard conditions Fig. 2 with image from Dash et al., 2014
atrium elongated, abnormal WT + MO1-septin15 standard conditions Fig. 2 from Dash et al., 2017
whole organism ins expression decreased amount, abnormal WT + MO1-septin15 control Fig. 8 with image from Dash et al., 2016
heart Z disc disorganized, abnormal WT + MO1-septin15 standard conditions Fig. 3 from Dash et al., 2017
endocrine pancreas has fewer parts of type pancreatic A cell, abnormal ia1Tg + MO1-septin15 standard conditions Fig. 3 with image from Dash et al., 2016
pancreas pancreatic A cell differentiation decreased occurrence, abnormal ia1Tg + MO1-septin15 standard conditions Fig. 3 with image from Dash et al., 2016
exocrine pancreas development decreased process quality, abnormal jh1Tg + MO1-septin15 standard conditions Fig. 4 with image from Dash et al., 2016
islet cell differentiation decreased process quality, abnormal jh1Tg + MO1-septin15 standard conditions Fig. 5 with image from Dash et al., 2016
exocrine pancreas malformed, abnormal jh1Tg + MO1-septin15 standard conditions Fig. 4 with image from Dash et al., 2016
pronephric tubule motile cilium decreased length, abnormal li1Tg + MO1-septin15 standard conditions Fig. 5 with image from Dash et al., 2014
cilium assembly decreased process quality, abnormal li1Tg + MO1-septin15 standard conditions Fig. 5 with image from Dash et al., 2014
gut epithelium EGFP expression mislocalised, abnormal nl1Tg + MO1-septin15 chemical treatment by environment: DAPT Fig. 7 with image from Dash et al., 2016
endocrine pancreas development decreased process quality, abnormal nl1Tg + MO1-septin15 chemical treatment by environment: DAPT Fig. 7 with image from Dash et al., 2016
intrapancreatic duct ins expression mislocalised, abnormal nl1Tg + MO1-septin15 control Fig. 7 with image from Dash et al., 2016
exocrine pancreas EGFP expression mislocalised, abnormal nl1Tg + MO1-septin15 control Fig. 7 with image from Dash et al., 2016
intrapancreatic duct EGFP expression mislocalised, abnormal nl1Tg + MO1-septin15 control Fig. 7 with image from Dash et al., 2016
gut epithelium ins expression mislocalised, abnormal nl1Tg + MO1-septin15 control Fig. 7 with image from Dash et al., 2016
endocrine pancreas development decreased process quality, abnormal nl1Tg + MO1-septin15 control Fig. 7 with image from Dash et al., 2016
gut epithelium EGFP expression mislocalised, abnormal nl1Tg + MO1-septin15 control Fig. 7 with image from Dash et al., 2016
exocrine pancreas EGFP expression mislocalised, abnormal nl1Tg + MO1-septin15 chemical treatment by environment: DAPT Fig. 7 with image from Dash et al., 2016
Citations
Your Input Welcome
We welcome your input and comments. Please use this form to recommend updates to the information in ZFIN. We appreciate as much detail as possible and references as appropriate. We will review your comments promptly.
Please check the highlighted fields and try again.
Thank you for submitting comments. Your input has been emailed to ZFIN curators who may contact you if additional information is required.
Oops. Something went wrong. Please try again later.