Morpholino

MO1-eaf1

ID
ZDB-MRPHLNO-090820-4
Name
MO1-eaf1
Previous Names
  • Eaf1-MO1 (1)
Target
Sequence
5' - GCGGCGGGTTCGAGCTGCCGTTCAT - 3'
ZFIN BLAST NCBI BLAST Ensembl UCSC BLAT
Disclaimer
Although ZFIN verifies reagent sequence data, we recommend that you conduct independent sequence analysis before ordering any reagent.
Note
Translation blocking.
Genome Resources
None
Target Location
Genomic Features
No data available
Expression
Gene expression in Wild Types + MO1-eaf1
Expressed Gene Anatomy Figures
cdx4 Fig. S3 with image from Liu et al., 2013
cmlc1 Fig. 6 from Liu et al., 2009
ctslb Fig. 2 from Liu et al., 2009
dlx3b Fig. 2 from Liu et al., 2009
foxa3 Fig. S1 from Liu et al., 2017
foxi1 Fig. S1 from Liu et al., 2017
foxo3b Fig. 7 from Liu et al., 2009
gata2a Fig. S1 from Liu et al., 2017
gata5 Fig. S1 from Liu et al., 2017
Fig. 6 from Liu et al., 2009
myod1 Fig. 3 from Liu et al., 2009
ndr1 Fig. S3 with image from Liu et al., 2013
otx1 Fig. 3 from Liu et al., 2009
six3b Fig. 1 with image from Liu et al., 2013
tbx6 Fig. S3 with image from Liu et al., 2013
tbxta Fig. 2,  Fig. 3 from Liu et al., 2009
wnt4 Fig. 4 with image from Wan et al., 2010
zic1 Fig. 2 with image from Liu et al., 2013
Phenotype
Phenotype resulting from MO1-eaf1
Phenotype Fish Figures
adaxial cell position, abnormal AB + MO1-eaf1 Fig. 3 from Liu et al., 2009
axial chorda mesoderm decreased length, abnormal AB + MO1-eaf1 Fig. 3 from Liu et al., 2009
convergent extension involved in axis elongation disrupted, abnormal AB + MO1-eaf1 Fig. 2,  Fig. 3 from Liu et al., 2009
convergent extension involved in organogenesis disrupted, abnormal AB + MO1-eaf1 Fig. 6 from Liu et al., 2009
head decreased size, abnormal AB + MO1-eaf1 Fig. 2 from Liu et al., 2009
heart development disrupted, abnormal AB + MO1-eaf1 Fig. 6 from Liu et al., 2009
muscle cell migration disrupted, abnormal AB + MO1-eaf1 Fig. 6 from Liu et al., 2009
neural plate increased width, abnormal AB + MO1-eaf1 Fig. 3 from Liu et al., 2009
neuroectoderm anterior region decreased size, abnormal WT + MO1-eaf1 Fig. 1 with image,  Fig. 2 with image from Liu et al., 2013
post-vent region decreased length, abnormal AB + MO1-eaf1 Fig. 2 from Liu et al., 2009
presumptive ectoderm gata2a expression decreased amount, abnormal AB + MO1-eaf1 Fig. S1 from Liu et al., 2017
presumptive ectoderm foxi1 expression decreased amount, abnormal AB + MO1-eaf1 Fig. S1 from Liu et al., 2017
presumptive ectoderm foxi1 expression decreased distribution, abnormal AB + MO1-eaf1 Fig. S1 from Liu et al., 2017
presumptive endoderm foxa3 expression increased amount, abnormal AB + MO1-eaf1 Fig. S1 from Liu et al., 2017
presumptive endoderm gata5 expression increased amount, abnormal AB + MO1-eaf1 Fig. S1 from Liu et al., 2017
transforming growth factor beta receptor signaling pathway decreased process quality, abnormal AB + MO1-eaf1 Fig. 7 from Liu et al., 2017
whole organism decreased length, abnormal AB + MO1-eaf1 Fig. 2 from Liu et al., 2009
Phenotype of all Fish created by or utilizing MO1-eaf1
Phenotype Fish Conditions Figures
presumptive endoderm foxa3 expression increased amount, abnormal AB + MO1-eaf1 standard conditions Fig. S1 from Liu et al., 2017
transforming growth factor beta receptor signaling pathway decreased process quality, abnormal AB + MO1-eaf1 standard conditions Fig. 7 from Liu et al., 2017
muscle cell migration disrupted, abnormal AB + MO1-eaf1 standard conditions Fig. 6 from Liu et al., 2009
heart development disrupted, abnormal AB + MO1-eaf1 standard conditions Fig. 6 from Liu et al., 2009
neural plate increased width, abnormal AB + MO1-eaf1 standard conditions Fig. 3 from Liu et al., 2009
whole organism decreased length, abnormal AB + MO1-eaf1 standard conditions Fig. 2 from Liu et al., 2009
presumptive ectoderm foxi1 expression decreased distribution, abnormal AB + MO1-eaf1 standard conditions Fig. S1 from Liu et al., 2017
head decreased size, abnormal AB + MO1-eaf1 standard conditions Fig. 2 from Liu et al., 2009
convergent extension involved in axis elongation disrupted, abnormal AB + MO1-eaf1 standard conditions Fig. 2,  Fig. 3 from Liu et al., 2009
convergent extension involved in organogenesis disrupted, abnormal AB + MO1-eaf1 standard conditions Fig. 6 from Liu et al., 2009
post-vent region decreased length, abnormal AB + MO1-eaf1 standard conditions Fig. 2 from Liu et al., 2009
presumptive ectoderm foxi1 expression decreased amount, abnormal AB + MO1-eaf1 standard conditions Fig. S1 from Liu et al., 2017
adaxial cell position, abnormal AB + MO1-eaf1 standard conditions Fig. 3 from Liu et al., 2009
presumptive ectoderm gata2a expression decreased amount, abnormal AB + MO1-eaf1 standard conditions Fig. S1 from Liu et al., 2017
presumptive endoderm gata5 expression increased amount, abnormal AB + MO1-eaf1 standard conditions Fig. S1 from Liu et al., 2017
axial chorda mesoderm decreased length, abnormal AB + MO1-eaf1 standard conditions Fig. 3 from Liu et al., 2009
neuroectoderm anterior region decreased size, abnormal WT + MO1-eaf1 standard conditions Fig. 1 with image,  Fig. 2 with image from Liu et al., 2013
convergent extension involved in axis elongation disrupted, abnormal AB + MO1-eaf1 + MO1-eaf2 standard conditions Fig. 2,  Fig. 3,  Fig. 4,  Fig. 9 from Liu et al., 2009
presumptive endoderm gata5 expression increased distribution, abnormal AB + MO1-eaf1 + MO1-eaf2 standard conditions Fig. 1,  Fig. 6 from Liu et al., 2017
neural plate increased width, abnormal AB + MO1-eaf1 + MO1-eaf2 standard conditions Fig. 3 from Liu et al., 2009
whole organism decreased length, abnormal AB + MO1-eaf1 + MO1-eaf2 standard conditions Fig. 2,  Fig. 9 from Liu et al., 2009
convergent extension involved in gastrulation disrupted, abnormal AB + MO1-eaf1 + MO1-eaf2 standard conditions Fig. 4 from Liu et al., 2009
endoderm sox32 expression increased distribution, abnormal AB + MO1-eaf1 + MO1-eaf2 standard conditions Fig. 2 from Liu et al., 2017
presumptive mesoderm tbxta expression increased distribution, abnormal AB + MO1-eaf1 + MO1-eaf2 standard conditions Fig. 1,  Fig. 6 from Liu et al., 2017
adaxial cell position, abnormal AB + MO1-eaf1 + MO1-eaf2 standard conditions Fig. 3 from Liu et al., 2009
prechordal plate mislocalised posteriorly, abnormal AB + MO1-eaf1 + MO1-eaf2 standard conditions Fig. 3 from Liu et al., 2009
pancreas development disrupted, abnormal AB + MO1-eaf1 + MO1-eaf2 standard conditions Fig. 6 from Liu et al., 2009
presumptive endoderm mixl1 expression increased distribution, abnormal AB + MO1-eaf1 + MO1-eaf2 standard conditions Fig. 1 from Liu et al., 2017
whole organism morphology, abnormal AB + MO1-eaf1 + MO1-eaf2 standard conditions Fig. 6 from Liu et al., 2017
presumptive ectoderm foxi1 expression decreased distribution, abnormal AB + MO1-eaf1 + MO1-eaf2 standard conditions Fig. 1 from Liu et al., 2017
muscle cell migration disrupted, abnormal AB + MO1-eaf1 + MO1-eaf2 standard conditions Fig. 6 from Liu et al., 2009
eye fused with eye, abnormal AB + MO1-eaf1 + MO1-eaf2 standard conditions Fig. 2,  Fig. 9 from Liu et al., 2009
heart development disrupted, abnormal AB + MO1-eaf1 + MO1-eaf2 standard conditions Fig. 6,  Fig. 9 from Liu et al., 2009
mesoderm lft1 expression increased distribution, abnormal AB + MO1-eaf1 + MO1-eaf2 standard conditions Fig. 2 from Liu et al., 2017
whole organism tp53 expression decreased amount, abnormal AB + MO1-eaf1 + MO1-eaf2 standard conditions Fig. 6 from Liu et al., 2017
post-vent region decreased length, abnormal AB + MO1-eaf1 + MO1-eaf2 standard conditions Fig. 2 from Liu et al., 2009
presumptive mesoderm lft1 expression increased distribution, abnormal AB + MO1-eaf1 + MO1-eaf2 standard conditions Fig. 2 from Liu et al., 2017
presumptive mesoderm increased width, abnormal AB + MO1-eaf1 + MO1-eaf2 standard conditions Fig. 5 from Liu et al., 2009
convergent extension involved in organogenesis disrupted, abnormal AB + MO1-eaf1 + MO1-eaf2 standard conditions Fig. 6,  Fig. 9 from Liu et al., 2009
head decreased size, abnormal AB + MO1-eaf1 + MO1-eaf2 standard conditions Fig. 2,  Fig. 9 from Liu et al., 2009
presumptive endoderm sox32 expression increased distribution, abnormal AB + MO1-eaf1 + MO1-eaf2 standard conditions Fig. 1 from Liu et al., 2017
presumptive endoderm increased size, abnormal AB + MO1-eaf1 + MO1-eaf2 standard conditions Fig. 5 from Liu et al., 2009
segmental plate decreased length, abnormal AB + MO1-eaf1 + MO1-eaf2 standard conditions Fig. 3 from Liu et al., 2009
axial chorda mesoderm decreased length, abnormal AB + MO1-eaf1 + MO1-eaf2 standard conditions Fig. 3 from Liu et al., 2009
presumptive mesoderm tbxta expression amount, ameliorated AB + MO1-eaf1 + MO1-eaf2 + MO4-tp53 standard conditions Fig. 6 from Liu et al., 2017
presumptive endoderm gata5 expression amount, ameliorated tdgf1tz257/tz257 + MO1-eaf1 + MO1-eaf2 standard conditions Fig. 3 from Liu et al., 2017
presumptive endoderm sox32 expression amount, ameliorated tdgf1tz257/tz257 + MO1-eaf1 + MO1-eaf2 standard conditions Fig. 3 from Liu et al., 2017
presumptive endoderm gata5 expression amount, ameliorated tp53zdf1/zdf1 + MO1-eaf1 + MO1-eaf2 standard conditions Fig. 6 from Liu et al., 2017
whole organism morphology, ameliorated tp53zdf1/zdf1 + MO1-eaf1 + MO1-eaf2 standard conditions Fig. 6 from Liu et al., 2017
neuroectoderm anterior region increased size, abnormal w32Tg + MO1-eaf1 heat shock Fig. 2 with image from Liu et al., 2013
Citations
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