Gene

cmlc1

ID

ZDB-GENE-030522-1

Name

cardiac myosin light chain-1

Symbol

cmlc1 Nomenclature History

Previous Names

laz (1)
lazy susan (1)
zgc:103441

Type

protein_coding_gene

Location

Chr: 5 Mapping Details/Browsers

Description

Predicted to have calcium ion binding activity. Involved in heart contraction; heart morphogenesis; and myofibril assembly. Human ortholog(s) of this gene implicated in familial atrial fibrillation. Is expressed in heart primordium; mesoderm; pericardial region; and somite. Orthologous to human MYL4 (myosin light chain 4).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

23 figures from 18 publications

Cross-Species Comparison

High Throughput Data

GEO (1)

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Thisse Expression Data

No data available

Wild Type Expression Summary

Phenotype

All Phenotype Data: 14 figures from 9 publications
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With cmlc1 Human Ortholog

No data available

Associated With cmlc1 Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Domain	IPR002048	EF-hand domain
Homologous_superfamily	IPR011992	EF-hand domain pair

Domain Details Per Protein

Protein	Length	EF-hand domain	EF-hand domain pair
UniProtKB:A0A8N7UZM3 InterPro	196
UniProtKB:Q5XJC3 InterPro	196

Transcripts

Genome Browsers

Type	Name	Annotation Method	Has Havana Data	Length (nt)	Analysis
mRNA	cmlc1-201 (1) Ensembl	Ensembl		796 nt	Select Tool

Interactions and Pathways

No data available

Antibodies

No data available

Plasmids

No data available

Constructs

Marker Relationships

Sequences

Orthology

Comparative Orthology: Alliance
Gene Tree: Ensembl

Citations