FIGURE

Fig 2

ID

ZDB-FIG-241219-151

Publication

Chakraborty et al., 2024 - Functional investigation suggests CNTNAP5 involvement in glaucomatous neurodegeneration obtained from a GWAS in primary angle closure glaucoma

Other Figures

All Figure Page

Back to All Figure Page

Fig 2

A. Variant detailed view of rs2553658 and rs17011429 in HaploReg. The regulatory motif TCF4 altered in reference and alternative allele of rs2553658. B. The data was drawn for a total of 3 biological replicates considering triplicate technical replicates for each biological experiments representing three different plasmid preparations (pGL3 SV40 minimal promoter vector) transfected in to HEK293T cells grown in 24-well plates. The height of the bar shows the mean value of all the 3 experiments, while error bars are depicting SE. The 4C plot of genomic region of CNTNAP5 (chr2:125,083,095–125,084,384) showing the FIREs, ChIP-Seq data and Hi-C counts in DPLC (C) and NPC (D) from HUGIn. The ratio of observed read counts to expected read counts is higher in NPC and is also statistically more significant than in DPLC (E).

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image. Full text @ PLoS Genet.