ZFIN Image: Chakraborty et al., 2024, Fig 2

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Figure Caption

Fig 2

A. Variant detailed view of rs2553658 and rs17011429 in HaploReg. The regulatory motif TCF4 altered in reference and alternative allele of rs2553658. B. The data was drawn for a total of 3 biological replicates considering triplicate technical replicates for each biological experiments representing three different plasmid preparations (pGL3 SV40 minimal promoter vector) transfected in to HEK293T cells grown in 24-well plates. The height of the bar shows the mean value of all the 3 experiments, while error bars are depicting SE. The 4C plot of genomic region of CNTNAP5 (chr2:125,083,095–125,084,384) showing the FIREs, ChIP-Seq data and Hi-C counts in DPLC (C) and NPC (D) from HUGIn. The ratio of observed read counts to expected read counts is higher in NPC and is also statistically more significant than in DPLC (E).

Acknowledgments

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