FIGURE

Figure 2

ID

ZDB-FIG-230709-10

Publication

Hoareau et al., 2023 - Characterization of the Zebrafish Elastin a (elna^sa12235) Mutant: A New Model of Elastinopathy Leading to Heart Valve Defects

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Figure 2

elna mutants have a shorter life expectancy. (A) Zebrafish survival from 3 independent clutches resulting from the crossing of heterozygous (elna ^sa12235/+) fish was recorded after genotyping, from 10–11 mpf to 15–22 mpf (WT = 27; HET = 78; MUT = 41 zebrafish). Survival curves were compared using the log-rank Mantel-Cox test and the Log-rank test for trend; * p < 0.05. (B,C) Weight and size of fish were measured at 11 and 20 mpf and expressed as a body mass index (BMI). Data were analyzed by Kruskal–Wallis test; ns = non-significant; mpf = months post fertilization; WT = wild type (elna^+/+); HET = heterozygous (elna ^sa12235/+); MUT = mutant (elna ^{sa12235/ sa12235}).

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Fish:	elna^{sa12235/sa12235} elna^sa12235/+
Observed In:	whole organism
Stage:	Adult

Phenotype Detail

Acknowledgments

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