FIGURE

Fig. 5

ID

ZDB-FIG-230125-25

Publication

Bek et al., 2021 - Lrp5 mutant and crispant zebrafish faithfully model human osteoporosis, establishing the zebrafish as a platform for CRISPR-based functional screening of osteoporosis candidate genes

Other Figures

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Fig. 5

ZFIN is incorporating published figure images and captions as part of an ongoing project. Figures from some publications have not yet been curated, or are not available for display because of copyright restrictions.

Expression Data

Genes:	axin2 dkk1a dkk1b GFP lef1 tcf7
Fish:	ia4Tg (AB) pd64Tg (AB) ia4Tg + CRISPR3-lrp5 (AB) pd64Tg + CRISPR3-lrp5 (AB) lrp5^{sa11097/sa11097}; ia4Tg (AB) lrp5^{sa11097/sa11097}; pd64Tg (AB)
Condition:	amputation: caudal fin
Knockdown Reagent:	CRISPR3-lrp5
Anatomical Term:	caudal fin blastema
Stage:	Adult

Expression Detail

Antibody Labeling

Phenotype Data

Fish:	lrp5^{sa11097/sa11097} (AB) AB + CRISPR3-lrp5 ia4Tg + CRISPR3-lrp5 (AB) pd64Tg + CRISPR3-lrp5 (AB) lrp5^{sa11097/sa11097}; ia4Tg (AB) lrp5^{sa11097/sa11097}; pd64Tg (AB)
Condition:	amputation: caudal fin
Knockdown Reagent:	CRISPR3-lrp5
Observed In:	caudal fin blastema caudal fin principal ray
Stage:	Adult

Phenotype Detail

Acknowledgments

Full text @ J. Bone Miner. Res.