Gene

tcf7

ID
ZDB-GENE-050222-4
Name
transcription factor 7
Symbol
tcf7 Nomenclature History
Previous Names
None
Type
protein_coding_gene
Location
Chr: 21 Mapping Details/Browsers
Description
Predicted to have DNA-binding transcription factor activity; RNA polymerase II cis-regulatory region sequence-specific DNA binding activity; and beta-catenin binding activity. Involved in pectoral fin development; regulation of transcription by RNA polymerase II; and spinal cord dorsal/ventral patterning. Predicted to localize to nucleus and transcription factor complex. Is expressed in several structures, including dermal bone; nervous system; optic cup; pectoral fin bud; and prechordal plate. Orthologous to human TCF7 (transcription factor 7).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
23 figures from 17 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
No data available
Wild Type Expression Summary
Phenotype
All Phenotype Data
3 figures from 3 publications
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With tcf7 Human Ortholog
No data available
Associated With tcf7 Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR009071 High mobility group box domain
Domain IPR013558 CTNNB1 binding, N-teminal
Family IPR024940 Transcription factor TCF/LEF
Homologous_superfamily IPR027397 Catenin binding domain superfamily
Homologous_superfamily IPR036910 High mobility group box domain superfamily
Domain Details Per Protein
Protein Length Catenin binding domain superfamily CTNNB1 binding, N-teminal High mobility group box domain High mobility group box domain superfamily Transcription factor TCF/LEF
UniProtKB:Q5PU93 355
Transcripts
Genome Browsers
Type Name Annotation Method Has Havana Data Length (nt) Analysis
mRNA tcf7-201 (1) Ensembl 803 nt
mRNA tcf7-202 (1) Ensembl 924 nt
mRNA tcf7-203 (1) Ensembl 939 nt
mRNA tcf7-204 (1) Ensembl 767 nt
mRNA tcf7-205 (1) Ensembl 792 nt
mRNA tcf7-206 (1) Ensembl 1,634 nt
mRNA tcf7-207 (1) Ensembl 1,327 nt
mRNA tcf7-208 (1) Ensembl 1,643 nt
mRNA tcf7-209 (1) Ensembl 1,580 nt
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations