Gene
dkk1a
- ID
- ZDB-GENE-090313-406
- Name
- dickkopf WNT signaling pathway inhibitor 1a
- Symbol
- dkk1a Nomenclature History
- Previous Names
-
- si:dkeyp-86d6.1
- Type
- protein_coding_gene
- Location
- Chr: 13 Mapping Details/Browsers
- Description
- Predicted to have co-receptor binding activity and receptor antagonist activity. Involved in neuromast development and sensory epithelium regeneration. Predicted to localize to extracellular space. Human ortholog(s) of this gene implicated in anodontia. Is expressed in anterior segment eye; retinal inner nuclear layer; and retinal outer nuclear layer. Orthologous to human DKK1 (dickkopf WNT signaling pathway inhibitor 1).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 11 figures from 10 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Domain | IPR006796 | Dickkopf, N-terminal cysteine-rich |
| Domain | IPR047304 | Dickkopf-related protein 1, second cysteine-rich domain |
| Domain | IPR048499 | Dickkopf-related protein 1/2/4, C-terminal subdomain 2 |
| Domain | IPR048500 | Dickkopf-related protein 1/2/4, C-terminal subdomain 1 |
| Family | IPR039863 | Dickkopf related protein 1-4 |
Domain Details Per Protein
| Protein | Length | Dickkopf, N-terminal cysteine-rich | Dickkopf-related protein 1/2/4, C-terminal subdomain 1 | Dickkopf-related protein 1/2/4, C-terminal subdomain 2 | Dickkopf related protein 1-4 | Dickkopf-related protein 1, second cysteine-rich domain |
|---|---|---|---|---|---|---|
|
UniProtKB:A0A8M1P605
|
247 | |||||
|
UniProtKB:A8WGT5
|
255 |
Interactions and Pathways
No data available
Plasmids
No data available