FIGURE

Fig. 8

ID

ZDB-FIG-210610-25

Publication

Yang et al., 2021 - Investigating the role of dachshund b in the development of the pancreatic islet in zebrafish

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Fig. 8

Zebrafish embryos that were co-injected with 4 ng splice-blocking dachb-morpholino (dachb-MO-S) + 4 ng p53-MO showed an altered expression of a number of other genes at 30 h post-fertilization. Embryos were either uninjected or else they were injected with 4 ng p53-MO or with 4 ng dachb-MO-S + 4 ng p53-MO and then the reverse transcription polymerase chain reaction was carried out to determine any changes in the expression of various (a) pancreas hormone-related genes; (b,c) regulators of pancreas development; and (c) cell cycle genes.The data are presented as the mean ± standard error of four experiments conducted per treatment. The asterisks indicate p53-MO + dachb-MO data that are significantly different from the p53-MO alone injected controls at P < 0.05* using the Mann–Whitney U-test.

Expression Data

Genes:	arxa ccnd1 cdkn1bb gcga ins insb insm1a insm1b isl1a mnx1 neurod1 neurog3 nkx6.1 nkx6.2 pax6a pax6b pdx1 prss1 ptf1a rad51 sst2
Fish:	AB AB + MO2-dachb + MO4-tp53
Knockdown Reagents:	MO2-dachb MO4-tp53
Anatomical Term:	whole organism
Stage:	Prim-15

Expression Detail

Antibody Labeling

Phenotype Data

Fish:	AB + MO2-dachb + MO4-tp53
Knockdown Reagents:	MO2-dachb MO4-tp53
Observed In:	whole organism
Stage:	Prim-15

Phenotype Detail

Acknowledgments

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