Gene
neurog3
- ID
- ZDB-GENE-010608-4
- Name
- neurogenin 3
- Symbol
- neurog3 Nomenclature History
- Previous Names
- Type
- protein_coding_gene
- Location
- Chr: 13 Mapping Details/Browsers
- Description
- Predicted to have protein dimerization activity. Predicted to be involved in endocrine pancreas development; neurogenesis; and regulation of transcription, DNA-templated. Human ortholog(s) of this gene implicated in congenital malabsorptive diarrhea 4; glucose intolerance; and type 2 diabetes mellitus. Is expressed in endocrine pancreas; gut; and hypothalamus. Orthologous to human NEUROG3 (neurogenin 3).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 5 figures from 5 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| congenital malabsorptive diarrhea 4 | Alliance | Diarrhea 4, malabsorptive, congenital | 610370 |
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Length | Basic helix-loop-helix transcription factors | Helix-loop-helix DNA-binding domain superfamily | Myc-type, basic helix-loop-helix (bHLH) domain | Neurogenin-3, basic helix-loop-helix domain |
|---|---|---|---|---|---|
|
UniProtKB:B3DFN6
|
208 | ||||
|
UniProtKB:Q9DG56
|
208 |
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
neurog3-201
(1)
|
Ensembl | 1,028 nt | ||
| mRNA |
neurog3-202
(1)
|
Ensembl | 846 nt |
Interactions and Pathways
No data available
Plasmids
No data available