Gene
insb
- ID
- ZDB-GENE-040113-2
- Name
- preproinsulin b
- Symbol
- insb Nomenclature History
- Previous Names
-
- zfins2 (1)
- Type
- protein_coding_gene
- Location
- Chr: 14 Mapping Details/Browsers
- Description
- Predicted to have hormone activity. Predicted to be involved in glucose metabolic process. Predicted to localize to extracellular region. Human ortholog(s) of this gene implicated in diabetic retinopathy; glucose metabolism disease (multiple); insulinoma; and pancreatic cancer. Is expressed in several structures, including blastomere; dermal bone; digestive system; kidney; and shield. Orthologous to human INS (insulin).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 17 figures from 11 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Length | Insulin | Insulin, conserved site | Insulin family | Insulin-like | Insulin-like superfamily |
|---|---|---|---|---|---|---|
|
UniProtKB:A0A140LFX1
|
151 | |||||
|
UniProtKB:A0A8M6Z2M5
|
167 | |||||
|
UniProtKB:Q2QAJ9
|
107 |
Interactions and Pathways
Plasmids
No data available