FIGURE

Figure 6

ID

ZDB-FIG-210130-21

Publication

Brunal et al., 2021 - Effects of Constitutive and Acute Connexin 36 Deficiency on Brain-Wide Susceptibility to PTZ-Induced Neuronal Hyperactivity

Other Figures

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Figure 6

Whole-brain activity of cx35.5-/- animals treated with mefloquine vs. DMSO. Dorsal and lateral views of zebrafish larvae brain are shown. Images show regions with significantly increased (green) or decreased (magenta) activity in cx35.5-/- animals treated with mefloquine compared to cx35.5-/- animals treated with DMSO. (A) Embryo medium (0 mM PTZ) (cx35.5-/- mefloquine n = 9, cx35.5-/- DMSO n = 11). (B) 5 mM PTZ (cx35.5-/- mefloquine n = 11, cx35.5-/- DMSO n = 11). (C) 20 mM PTZ (cx35.5-/- mefloquine n = 10, cx35.5-/- DMSO n = 7). Mef: mefloquine.

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Fish:	mitfa^w2/w2; gjd2a^fh437/fh437
Conditions:	chemical treatment by environment: Mefloquine hydrochloride chemical treatment by environment: Mefloquine hydrochloride
Observed In:	area postrema neuronal action potential habenula neuronal action potential hindbrain neuronal action potential inferior olive neuronal action potential olfactory bulb neuronal action potential rhombomere 7 neuronal action potential telencephalon neuronal action potential ventral telencephalon neuronal action potential
Stage:	Day 6

Phenotype Detail

Acknowledgments

This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image. Full text @ Front. Mol. Neurosci.