FIGURE

Figure 2

ID

ZDB-FIG-210130-17

Publication

Brunal et al., 2021 - Effects of Constitutive and Acute Connexin 36 Deficiency on Brain-Wide Susceptibility to PTZ-Induced Neuronal Hyperactivity

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Figure 2

Activated caspase 3 positive cells by major brain division, comparing cx35.5-/- vs. wild type with and without PTZ. Representative sum stack projections of wild-type and cx35.5-/- larvae treated with media (A, B) or PTZ (D, E) and stained with anti-activated caspase-3. (C–F) Graphs depicting the number of activated caspase-3 positive cells in the rhombencephalon, mesencephalon, telencephalon, and diencephalon in wild-type (black) vs. cx35.5-/- (red) fish with treatment with (C) embryo medium (vehicle) or (F) PTZ. Data were analyzed using an unpaired t-test with Holm-Sidak's correction for multiple comparisons. Embryo medium (vehicle) treatment, wild type n = 5, cx35.5-/- n = 10. PTZ treatment, wild type n = 6, cx35.5-/- n = 8.

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Fish:	mitfa^w2/w2; gjd2a^fh437/fh437
Condition:	chemical treatment by environment: pentetrazol
Observed In:	diencephalon apoptotic process hindbrain apoptotic process midbrain apoptotic process telencephalon apoptotic process
Stage:	Day 6

Phenotype Detail

Acknowledgments

This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image. Full text @ Front. Mol. Neurosci.