GeneTitan array analysis of the expression profile of wild-type zebrafish following different treatments. (A) Venn diagram of upregulation of genes in WT zebrafish irradiation and Oligo-Fucoidan pretreatment (OF + R) versus irradiation alone (R), overlapping with downregulated in irradiation (R) compare to no radiation (control). (B) The heatmap of genes that were upregulated in Oligo-Fucoidan pretreatment but downregulated by irradiation. First batch is 40 Gy (1), and second batch is 10 Gy (2). (C) Gene ontology analysis of Oligo-Fucoidan-induced genes in WT irradiation (D) Venn diagram of downregulation of genes in WT zebrafish irradiation and Oligo-Fucoidan pretreatment (OF + R) versus irradiation alone (R), overlapping with upregulated in irradiation (R) compared to no radiation (control). (E) The heatmap of genes that were downregulated in Oligo-Fucoidan pretreatment but upregulated by irradiation. First batch is 40 Gy (1), and second batch is 10 Gy (2). (F) Gene ontology analysis of Oligo-Fucoidan repressed genes in WT irradiation.
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