FIGURE

Figure 3—figure supplement 2.

ID

ZDB-FIG-200718-51

Publication

Özcan et al., 2020 - Sleep is bi-directionally modified by amyloid beta oligomers

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Figure 3—figure supplement 2.

<italic>adrb2a</italic> and <italic>pgrmc1</italic> mutations have small effects on baseline sleep:wake parameters.

(A–C’) Sleep and waking activity plots for larvae from pgrmc1^+/- in crosses. (A,A’) show representative 48 hr traces for the indicated genotypes. The ribbon represents ± SEM. (B–C’) Sleep and waking activity for each larva for all genotypes are plotted. The error bars represent the mean ± SEM. There is a trend to decreased waking activity in pgrmc1^-/- mutants compared to wild-type siblings. p=0.07, Kruskal-Wallis, Tukey-Kramer post-hoc. (D–F’) Sleep and waking activity plots for larvae from adrb2a^+/- in crosses. (D,D’) show 48 hr traces for all three genotypes. The ribbon represents ± SEM. (E–F’) Sleep and waking activity for the day and night are plotted for each larva. The error bars represent the mean ± SEM. Compared to both wild type and heterozygous siblings, adrb2a^-/- mutants have increased sleep during the day. *p≤0.05, Kruskal-Wallis, Tukey-Kramer post-hoc.

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

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