FIGURE

Fig. S3

ID

ZDB-FIG-190822-24

Publication

Pei et al., 2018 - Guided genetic screen to identify genes essential in the regeneration of hair cells and other tissues

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Fig. S3

Mutations tested that affected hair cell development as well as hair cell regeneration.

(A-C) Quantification of the development and regeneration of neuromast hair cells in the mutants homozygous for snrnp25 (A), hdac1 (B), and prps1a (C). Hair cell development was assayed at 5 dpf (except otherwise indicated). Hair cell regeneration was assayed by copper ablation at 5 dpf and regeneration at 7 dpf (labeled on graph as “regen”). Graph shows the mean and s.e.m. Control (ctrl) represents both wild type and heterozygotes, as no difference was observed between them. The difference between control and homozygous mutants is indicated. Asterisks indicate the difference is significant (p < 0.05). n. s. indicates the difference is not significant.

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Fish:	hdac1^{zf2150/zf2150} prps1a^{la015591Tg/la015591Tg} snrnp25^hg99/hg99
Condition:	chemical ablation: neuromast hair cell, chemical treatment by environment: copper(II) sulfate
Observed In:	neuromast development neuromast hair cell neuromast hair cell regeneration posterior lateral line neuromast
Stage Range:	Protruding-mouth to Days 7-13

Phenotype Detail

Acknowledgments

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