FIGURE

Fig. S4

ID

ZDB-FIG-190107-7

Publication

Blanco-Sánchez et al., 2018 - Grxcr1 Promotes Hair Bundle Development by Destabilizing the Physical Interaction between Harmonin and Sans Usher Syndrome Proteins

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Fig. S4

Mechanosensation is not affected in grxcr1 mutants. Related to Figure 2. (A) Percentage of larvae responding correctly to the startle response test or with a balance defect. The number of larvae analyzed was as follow: 104 grxcr1^+/+, 121 grxcr1^+/b1259, 43 grxcr1b1259/b1259, 112 grxcr1+/b1260, 70 grxcr1b1260/b1260. (B) Average intensity of FM1-43 signal within the hair bundles of inner ear hair cells in grxcr1^+/+ (n=20 larvae) and grxcr1^-/- (n=22 larvae). Incorporation of FM1-43 in the hair bundles of the hair cells of the anterior macula at 5 dpf in grxcr1^+/+ (C) and grxcr1-/- (D). (E) Average intensity of FM1-43 signal within the hair bundles of neuromast hair cells in grxcr1^+/+ (n=20 larvae) and grxcr1^-/- (n=22 larvae). Data were normalized to grxcr1^+/+. Data are represented as mean ± SEM.

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

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