FIGURE

Fig. 1

ID

ZDB-FIG-190107-1

Publication

Blanco-Sánchez et al., 2018 - Grxcr1 Promotes Hair Bundle Development by Destabilizing the Physical Interaction between Harmonin and Sans Usher Syndrome Proteins

Other Figures

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Fig. 1

Grxcr1 Is Required for Stereocilium Widening in the Anterior Macula

(A–C) Phalloidin staining of the whole anterior macula in grxcr1^+/+ (A), grxcr1^b1259/b1259 (B), and grxcr1^b1260/b1260 mutant larvae (C).

(D) Average number of hair bundles in grxcr1^+/+ (n = 41 larvae), grxcr1^b1259/b1259 (n = 35 larvae), and grxcr1^b1260/b1260 mutant larvae (n = 32 larvae).

(E) Number of TUNEL-positive cells in grxcr1^+/+ (n = 18 larvae) and grxcr1^−/− mutant larvae (n = 28 larvae).

(F) Average hair bundle width at half their height in grxcr1^+/+ (n = 40 larvae), grxcr1^b1259/b1259 (n = 34 larvae), and grxcr1^b1260/b1260 mutant larvae (n = 36 larvae).

Data are represented as mean ± SEM. ^∗p < 0.05, ^∗∗p < 0.01; 5 dpf.

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Fish:	grxcr1a^b1259/b1259 grxcr1a^b1260/b1260
Observed In:	hair cell anterior macula
Stage:	Day 5

Phenotype Detail

Acknowledgments

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