FIGURE

Fig. S1

ID

ZDB-FIG-150420-9

Publication

Paolini et al., 2015 - Asymmetric inheritance of the apical domain and self-renewal of retinal ganglion cell progenitors depend on Anillin function

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Fig. S1

Reciprocal regulation between Anillin and Ath5. (A) Ath5-/- (lakritz) mutant embryos retain anillin expression in the central retina where progenitors fail to exit the cell cycle and to differentiate into RGCs (highlighted by the cxcr4b expression in the wild-type retina). Scale bar: 21 µm. Anterior is always to the left, dorsal is to the top. (B) UCSC genome browser (https://genome.ucsc.edu/) overview of the anillin locus. Red-circled area shows the overlap between histone 3 lysine 4 monomethylation marks (indicative of cis-regulatory activity) at 24 hpf (blue) with Ath5 consensus binding site (black) 5 kb upstream of anillin transcription start site.

Expression Data

Genes:	anln cxcr4b
Fish:	AB atoh7^th241/th241
Anatomical Terms:	retina retinal ganglion cell
Stage:	Prim-15

Expression Detail

Antibody Labeling

Phenotype Data

Fish:	atoh7^th241/th241
Observed In:	retinal ganglion cell
Stage:	Prim-15

Phenotype Detail

Acknowledgments

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