FIGURE

Fig. 1

ID

ZDB-FIG-140717-10

Publication

Lele et al., 2002 - parachute/n-cadherin is required for morphogenesis and maintained integrity of the zebrafish neural tube

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Fig. 1

pac mutants exhibit abnormal brain and tail morphogenesis. (A,C,E,G) Wild-type siblings, (B,D,F,H,I) pac^fr7 mutants. (A,B) Eight-somite stage, frontal view, arrows in B indicate broadened neural tube at midbrain-hindbrain level. (C-I) 24 hpf. (C,D) lateral overview; arrows in D indicate sites of phenotypic defects in the midbrain-hindbrain region and tip of tail. (E,F) Magnification of head region; arrowheads in E,F indicates the position of the midbrain-hindbrain boundary, arrows in F indicate loose cell aggregates in ventricle. (G-I) Magnification of tip of tail; lateral view (G,H) and dorsal view (I); arrows in H,I indicate region with split dorsal fin.

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Fish:	cdh2^fr7/fr7
Observed In:	dorsal fin fold posterior side fourth ventricle hindbrain hindbrain dorsal region hindbrain neural keel midbrain midbrain dorsal region midbrain hindbrain boundary neural rod neuroepithelial cell neuron
Stage Range:	5-9 somites to Prim-5

Phenotype Detail

Acknowledgments

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