FIGURE

Fig. 9

ID

ZDB-FIG-140414-21

Publication

Johnson et al., 2014 - Kif11 dependent cell cycle progression in radial glial cells is required for proper neurogenesis in the zebrafish neural tube

Other Figures

All Figure Page

Back to All Figure Page

Fig. 9

Kif11 is required for secondary motorneurons but not primary motorneurons. (A–F) Visualization of primary motorneuron development in somite 11 over time using the Tg(mnx1:GFP) transgenic line. No difference in the formation of primary motorneurons was observed in STLC treated Tg(mnx1:GFP) transgenic embryos (D–F) as compared to control DMSO treated embryos (A–C). (G,H) Lateral view of the neural tube of Tg(gata2:EGFP) transgenic embryos at 48 hpf to assess secondary motorneurons in control DMSO treated (G) or STLC treated transgenic embryos from 5 to 48 hpf (H). (I) A significant decrease in GFP+ neurons was seen in STLC treated Tg(gata2:EGFP) embryos. Error bars delineate the standard error of the mean. Asterisks indicate a statistical significance (t-test, two tailed, assuming equal variances, p<0.05).

Expression Data

Gene:	GFP
Fish:	ml2Tg zf35Tg
Condition:	chemical treatment: pharmaceutical
Anatomical Terms:	primary motor neuron secondary motor neuron
Stage Range:	14-19 somites to High-pec

Expression Detail

Antibody Labeling

Phenotype Data

Fish:	zf35Tg
Condition:	chemical treatment: pharmaceutical
Observed In:	secondary motor neuron
Stage:	High-pec

Phenotype Detail

Acknowledgments

This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image.

Reprinted from Developmental Biology, 387(1), Johnson, K., Moriarty, C., Tania, N., Ortman, A., Dipietrantonio, K., Edens, B., Eisenman, J., Ok, D., Krikorian, S., Barragan, J., Golé, C., and Barresi, M.J., Kif11 dependent cell cycle progression in radial glial cells is required for proper neurogenesis in the zebrafish neural tube, 73-92, Copyright (2014) with permission from Elsevier. Full text @ Dev. Biol.