FIGURE

Fig. S1

ID

ZDB-FIG-131106-2

Publication

Hess et al., 2012 - Intravital Imaging of Thymopoiesis Reveals Dynamic Lympho-Epithelial Interactions

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Fig. S1

Initial colonization of the thymic rudiment in embryos depends on ikaros function

Projected images of fish double-transgenic for ikaros:eGFP and foxn1:mCherry experiments constructs were obtained at 98 hpf. Representative wild-type (ikaros^+/?; n=20) and ikaros-deficient (ikaros^-/-; n=12) embryos are shown. The green cells seen in the images of the mutant embryos are motile myeloid cells, which do not reside in the thymus and hence do not obscure the view onto the thymic epithelial rudiment (red). For further details see Figure 2 and text. Scale bars, 50μm for upper, and 20μm for lower panels.

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Fish:	ikzf1^{t24980/t24980}; fr101Tg; fr103Tg/fr103Tg
Observed In:	thymus development
Stage:	Day 4

Phenotype Detail

Acknowledgments

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Reprinted from Immunity, 36(2), Hess, I., and Boehm, T., Intravital Imaging of Thymopoiesis Reveals Dynamic Lympho-Epithelial Interactions, 298-309, Copyright (2012) with permission from Elsevier. Full text @ Immunity