FIGURE

Fig. 12

ID

ZDB-FIG-110920-80

Publication

Eames et al., 2011 - Mutations in fam20b and xylt1 Reveal That Cartilage Matrix Controls Timing of Endochondral Ossification by Inhibiting Chondrocyte Maturation

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Fig. 12

The ihha mutation is epistatic to bone, but not cartilage, phenotypes of fam20b and xylt1 mutants.

A–H, Alcian blue/Alizarin red-stained 6 dpf ceratohyals. Alcian blue staining was comparable between wild-type (A,E) and ihha mutant (B,F) cartilages, but was decreased in fam20b^b1127 (C) and xylt1^b1128 (G) single mutant, and in fam20b^b1127;ihha (D) and xylt1^b1128;ihha (H) double mutant, cartilages. Alizarin red staining of fam20b^b1127 (C) and xylt1^b1128 (D) chondral bones was abundant, while no such staining was observed in wild types (A,E), ihha mutants (B,F), or fam20b^b1127;ihha (D) and xylt1^b1128;ihha double mutants (H). Abbreviations: bsr = branchiostegal ray.

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Fish:	fam20b^b1127/b1127 (AB) ihha^{hu2131/hu2131} xylt1^b1128/b1128 (AB) fam20b^b1127/b1127; ihha^{hu2131/hu2131} (AB) ihha^{hu2131/hu2131}; xylt1^b1128/b1128 (AB)
Observed In:	ceratohyal cartilage perichondral bone
Stage:	Day 6

Phenotype Detail

Acknowledgments

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